MAP1S (microtubule associated protein 1S)

2014-11-01  

Identity

HGNC
MAP1S
LOCATION
19p13.11
LOCUSID
55201
ALIAS
BPY2IP1,C19orf5,MAP8,VCY2IP-1,VCY2IP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55201
MIM: 607573
HGNC: 15715
Ensembl: ENSG00000130479

Variants:

dbSNP: 55201
ClinVar: 55201
TCGA: ENSG00000130479
COSMIC: MAP1S

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130479ENST00000324096Q66K74
ENSG00000130479ENST00000544059Q66K74
ENSG00000130479ENST00000593593M0QX37
ENSG00000130479ENST00000594212M0QXE8
ENSG00000130479ENST00000594365M0QXK6
ENSG00000130479ENST00000594625M0QY41
ENSG00000130479ENST00000596637M0QYI5
ENSG00000130479ENST00000597000M0R1M7
ENSG00000130479ENST00000597735M0QXQ9
ENSG00000130479ENST00000600186M0R1J2
ENSG00000130479ENST00000600608M0QZ50

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
212629642011Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation.50
155282092005Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family.23
255052422015Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus.19
197594192009Dual function microtubule- and mitochondria-associated proteins mediate mitotic cell death.14
159078022005Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein.13
146275432004Identification and characterization of human VCY2-interacting protein: VCY2IP-1, a microtubule-associated protein-like protein.12
267018562016Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival.12
265400942015Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.11
190270082008The role of microtubule-associated protein 1S in SOCS3 regulation of IL-6 signaling.8
253007932014MAP1S controls microtubule stability throughout the cell cycle in human cells.8

Citation

Dessen P

MAP1S (microtubule associated protein 1S)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68793/map1s