Identity
HGNC
LOCATION
3q27.2
LOCUSID
ALIAS
LZK,MEKK13,MLK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9175
MIM: 604915
HGNC: 6852
Ensembl: ENSG00000073803
Variants:
dbSNP: 9175
ClinVar: 9175
TCGA: ENSG00000073803
COSMIC: MAP3K13
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| MAPK signaling pathway | KEGG | ko04010 |
| MAPK signaling pathway | KEGG | hsa04010 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35311629 | 2022 | Clinical significance of mitogen-activated protein kinase kinase kinases in hepatitis B virus -related hepatocellular carcinoma and underlying mechanism exploration. | 0 |
| 35311629 | 2022 | Clinical significance of mitogen-activated protein kinase kinase kinases in hepatitis B virus -related hepatocellular carcinoma and underlying mechanism exploration. | 0 |
| 31186535 | 2020 | The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor development. | 32 |
| 31186535 | 2020 | The MAP3K13-TRIM25-FBXW7α axis affects c-Myc protein stability and tumor development. | 32 |
| 28641113 | 2017 | Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons. | 74 |
| 28641113 | 2017 | Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons. | 74 |
| 26918941 | 2016 | microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13. | 20 |
| 26918941 | 2016 | microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13. | 20 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 12186766 | 2002 | Genomic organization and fine-mapping of the human leucine zipper-bearing kinase (LZK) gene. | 0 |
| 12186766 | 2002 | Genomic organization and fine-mapping of the human leucine zipper-bearing kinase (LZK) gene. | 0 |
Citation
Dessen P
MAP3K13 (mitogen-activated protein kinase kinase kinase 13)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43342/map3k13
