Identity
HGNC
LOCATION
12q24.12
LOCUSID
ALIAS
MAPKAP-K5,MK-5,MK5,PRAK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8550
MIM: 606723
HGNC: 6889
Ensembl: ENSG00000089022
Variants:
dbSNP: 8550
ClinVar: 8550
TCGA: ENSG00000089022
COSMIC: MAPKAPK5
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36581449 | 2023 | Consolidating the association of biallelic MAPKAPK5 pathogenic variants with a distinct syndromic neurodevelopmental disorder. | 1 |
| 36581449 | 2023 | Consolidating the association of biallelic MAPKAPK5 pathogenic variants with a distinct syndromic neurodevelopmental disorder. | 1 |
| 35064619 | 2022 | TLK1-mediated MK5-S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies. | 5 |
| 35468721 | 2022 | MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis. | 4 |
| 35575217 | 2022 | Expanding the novel MAPKAPK5-related developmental disorder's genotype-phenotype correlation: Patient report and 19 months of follow-up. | 2 |
| 35844789 | 2022 | The TTYH3/MK5 Positive Feedback Loop regulates Tumor Progression via GSK3-β/β-catenin signaling in HCC. | 4 |
| 35064619 | 2022 | TLK1-mediated MK5-S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies. | 5 |
| 35468721 | 2022 | MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis. | 4 |
| 35575217 | 2022 | Expanding the novel MAPKAPK5-related developmental disorder's genotype-phenotype correlation: Patient report and 19 months of follow-up. | 2 |
| 35844789 | 2022 | The TTYH3/MK5 Positive Feedback Loop regulates Tumor Progression via GSK3-β/β-catenin signaling in HCC. | 4 |
| 33442026 | 2021 | Biallelic truncating variants in MAPKAPK5 cause a new developmental disorder involving neurological, cardiac, and facial anomalies combined with synpolydactyly. | 3 |
| 33442026 | 2021 | Biallelic truncating variants in MAPKAPK5 cause a new developmental disorder involving neurological, cardiac, and facial anomalies combined with synpolydactyly. | 3 |
| 31578200 | 2019 | MK5 Regulates YAP Stability and Is a Molecular Target in YAP-Driven Cancers. | 21 |
| 31578200 | 2019 | MK5 Regulates YAP Stability and Is a Molecular Target in YAP-Driven Cancers. | 21 |
| 28941148 | 2017 | MK5: A novel regulator of cardiac fibroblast function? | 9 |
Citation
Dessen P
MAPKAPK5 (MAPK activated protein kinase 5)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41296/mapkapk5
