Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MAPKBP1 (mitogen-activated protein kinase binding protein 1)

Identity

Alias_namesmitogen activated protein kinase binding protein 1
Alias_symbol (synonym)KIAA0596
NPHP20
Other aliasJNKBP-1
JNKBP1
HGNC (Hugo) MAPKBP1
LocusID (NCBI) 23005
Atlas_Id 49923
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 41774434 and ends at 41827855 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KLHL3 (5q31.2) / MAPKBP1 (15q15.1)MAPKBP1 (15q15.1) / DLGAP1 (18p11.31)MAPKBP1 (15q15.1) / MAPKBP1 (15q15.1)
MAPKBP1 (15q15.1) / STX6 (1q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MAPKBP1   29536
Cards
Entrez_Gene (NCBI)MAPKBP1  23005  mitogen-activated protein kinase binding protein 1
AliasesJNKBP-1; JNKBP1; NPHP20
GeneCards (Weizmann)MAPKBP1
Ensembl hg19 (Hinxton)ENSG00000137802 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137802 [Gene_View]  ENSG00000137802 [Sequence]  chr15:41774434-41827855 [Contig_View]  MAPKBP1 [Vega]
ICGC DataPortalENSG00000137802
TCGA cBioPortalMAPKBP1
AceView (NCBI)MAPKBP1
Genatlas (Paris)MAPKBP1
WikiGenes23005
SOURCE (Princeton)MAPKBP1
Genetics Home Reference (NIH)MAPKBP1
Genomic and cartography
GoldenPath hg38 (UCSC)MAPKBP1  -     chr15:41774434-41827855 +  15q15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAPKBP1  -     15q15.1   [Description]    (hg19-Feb_2009)
GoldenPathMAPKBP1 - 15q15.1 [CytoView hg19]  MAPKBP1 - 15q15.1 [CytoView hg38]
ImmunoBaseENSG00000137802
Mapping of homologs : NCBIMAPKBP1 [Mapview hg19]  MAPKBP1 [Mapview hg38]
OMIM616786   617271   
Gene and transcription
Genbank (Entrez)AB011168 AB177850 AK091616 AK292414 AK302482
RefSeq transcript (Entrez)NM_001128608 NM_001265611 NM_014994
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAPKBP1
Cluster EST : UnigeneHs.513661 [ NCBI ]
CGAP (NCI)Hs.513661
Alternative Splicing GalleryENSG00000137802
Gene ExpressionMAPKBP1 [ NCBI-GEO ]   MAPKBP1 [ EBI - ARRAY_EXPRESS ]   MAPKBP1 [ SEEK ]   MAPKBP1 [ MEM ]
Gene Expression Viewer (FireBrowse)MAPKBP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23005
GTEX Portal (Tissue expression)MAPKBP1
Human Protein AtlasENSG00000137802-MAPKBP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60336   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60336  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60336
Splice isoforms : SwissVarO60336
PhosPhoSitePlusO60336
Domaine pattern : Prosite (Expaxy)WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)MAPKBP1
DMDM Disease mutations23005
Blocks (Seattle)MAPKBP1
SuperfamilyO60336
Human Protein Atlas [tissue]ENSG00000137802-MAPKBP1 [tissue]
Peptide AtlasO60336
HPRD17465
IPIIPI00783044   IPI00782945   IPI00943806   IPI00479587   IPI00167154   IPI00967332   IPI00963846   IPI00894236   IPI00965500   
Protein Interaction databases
DIP (DOE-UCLA)O60336
IntAct (EBI)O60336
FunCoupENSG00000137802
BioGRIDMAPKBP1
STRING (EMBL)MAPKBP1
ZODIACMAPKBP1
Ontologies - Pathways
QuickGOO60336
Ontology : AmiGOprotein binding  nucleus  cytoplasm  negative regulation of I-kappaB kinase/NF-kappaB signaling  mitotic spindle pole  negative regulation of defense response to bacterium  negative regulation of interleukin-8 secretion  
Ontology : EGO-EBIprotein binding  nucleus  cytoplasm  negative regulation of I-kappaB kinase/NF-kappaB signaling  mitotic spindle pole  negative regulation of defense response to bacterium  negative regulation of interleukin-8 secretion  
NDEx NetworkMAPKBP1
Atlas of Cancer Signalling NetworkMAPKBP1
Wikipedia pathwaysMAPKBP1
Orthology - Evolution
OrthoDB23005
GeneTree (enSembl)ENSG00000137802
Phylogenetic Trees/Animal Genes : TreeFamMAPKBP1
HOGENOMO60336
Homologs : HomoloGeneMAPKBP1
Homology/Alignments : Family Browser (UCSC)MAPKBP1
Gene fusions - Rearrangements
Fusion : QuiverMAPKBP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAPKBP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAPKBP1
dbVarMAPKBP1
ClinVarMAPKBP1
1000_GenomesMAPKBP1 
Exome Variant ServerMAPKBP1
ExAC (Exome Aggregation Consortium)ENSG00000137802
GNOMAD BrowserENSG00000137802
Varsome BrowserMAPKBP1
Genetic variants : HAPMAP23005
Genomic Variants (DGV)MAPKBP1 [DGVbeta]
DECIPHERMAPKBP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAPKBP1 
Mutations
ICGC Data PortalMAPKBP1 
TCGA Data PortalMAPKBP1 
Broad Tumor PortalMAPKBP1
OASIS PortalMAPKBP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAPKBP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAPKBP1
Mutations and Diseases : HGMDMAPKBP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAPKBP1
DgiDB (Drug Gene Interaction Database)MAPKBP1
DoCM (Curated mutations)MAPKBP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAPKBP1 (select a term)
intoGenMAPKBP1
Cancer3DMAPKBP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616786    617271   
Orphanet
DisGeNETMAPKBP1
MedgenMAPKBP1
Genetic Testing Registry MAPKBP1
NextProtO60336 [Medical]
TSGene23005
GENETestsMAPKBP1
Target ValidationMAPKBP1
Huge Navigator MAPKBP1 [HugePedia]
snp3D : Map Gene to Disease23005
BioCentury BCIQMAPKBP1
ClinGenMAPKBP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23005
Chemical/Pharm GKB GenePA142671479
Clinical trialMAPKBP1
Miscellaneous
canSAR (ICR)MAPKBP1 (select the gene name)
DataMed IndexMAPKBP1
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAPKBP1
EVEXMAPKBP1
GoPubMedMAPKBP1
iHOPMAPKBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:52:42 CET 2019
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