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MARCHF3 (membrane associated ring-CH-type finger 3)

Identity

Alias (NCBI)MARCH-III
MARCH3
RNF173
HGNC (Hugo) MARCHF3
HGNC Alias symbMGC48332
MARCH-III
RNF173
HGNC Previous namemembrane-associated ring finger (C3HC4) 3
 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
LocusID (NCBI) 115123
Atlas_Id 68810
Location 5q23.2  [Link to chromosome band 5q23]
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)MARCHF3   28728
Cards
Entrez_Gene (NCBI)MARCHF3    membrane associated ring-CH-type finger 3
AliasesMARCH-III; MARCH3; RNF173
GeneCards (Weizmann)MARCHF3
Ensembl hg19 (Hinxton)ENSG00000173926 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173926 [Gene_View]  ENSG00000173926 [Sequence]  - [Contig_View]  MARCHF3 [Vega]
ICGC DataPortalENSG00000173926
TCGA cBioPortalMARCHF3
AceView (NCBI)MARCHF3
Genatlas (Paris)MARCHF3
SOURCE (Princeton)MARCHF3
Genetics Home Reference (NIH)MARCHF3
Genomic and cartography
GoldenPath hg38 (UCSC)MARCHF3  -  
GoldenPath hg19 (UCSC)MARCHF3  -  
GoldenPathMARCHF3 - [CytoView hg19]  MARCHF3 - [CytoView hg38]
ImmunoBaseENSG00000173926
genome Data Viewer NCBIMARCHF3 [Mapview hg19]  
OMIM613333   
Gene and transcription
Genbank (Entrez)AF055007 AK000103 AK290129 BC047569 BC146948
RefSeq transcript (Entrez)NM_178450
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MARCHF3
Alternative Splicing GalleryENSG00000173926
Gene ExpressionMARCHF3 [ NCBI-GEO ]   MARCHF3 [ EBI - ARRAY_EXPRESS ]   MARCHF3 [ SEEK ]   MARCHF3 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCHF3 [ Firebrowse - Broad ]
GenevisibleExpression of MARCHF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115123
GTEX Portal (Tissue expression)MARCHF3
Human Protein AtlasENSG00000173926-MARCHF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UD3
Splice isoforms : SwissVarQ86UD3
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ86UD3
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCHF3
Blocks (Seattle)MARCHF3
SuperfamilyQ86UD3
Human Protein Atlas [tissue]ENSG00000173926-MARCHF3 [tissue]
Peptide AtlasQ86UD3
HPRD14362
IPIIPI00033653   IPI00967817   
Protein Interaction databases
DIP (DOE-UCLA)Q86UD3
IntAct (EBI)Q86UD3
BioGRIDMARCHF3
STRING (EMBL)MARCHF3
ZODIACMARCHF3
Ontologies - Pathways
QuickGOQ86UD3
Ontology : AmiGOubiquitin-protein transferase activity  lysosome  endosome  endocytosis  zinc ion binding  integral component of membrane  protein ubiquitination  protein ubiquitination  cytoplasmic vesicle membrane  early endosome membrane  intracellular membrane-bounded organelle  
Ontology : EGO-EBIubiquitin-protein transferase activity  lysosome  endosome  endocytosis  zinc ion binding  integral component of membrane  protein ubiquitination  protein ubiquitination  cytoplasmic vesicle membrane  early endosome membrane  intracellular membrane-bounded organelle  
NDEx NetworkMARCHF3
Atlas of Cancer Signalling NetworkMARCHF3
Wikipedia pathwaysMARCHF3
Orthology - Evolution
OrthoDB115123
GeneTree (enSembl)ENSG00000173926
Phylogenetic Trees/Animal Genes : TreeFamMARCHF3
HOGENOMQ86UD3
Homologs : HomoloGeneMARCHF3
Homology/Alignments : Family Browser (UCSC)MARCHF3
Gene fusions - Rearrangements
Fusion : QuiverMARCHF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCHF3 [hg38]
dbVarMARCHF3
ClinVarMARCHF3
MonarchMARCHF3
1000_GenomesMARCHF3 
Exome Variant ServerMARCHF3
GNOMAD BrowserENSG00000173926
Varsome BrowserMARCHF3
Genomic Variants (DGV)MARCHF3 [DGVbeta]
DECIPHERMARCHF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMARCHF3 
Mutations
ICGC Data PortalMARCHF3 
TCGA Data PortalMARCHF3 
Broad Tumor PortalMARCHF3
OASIS PortalMARCHF3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMARCHF3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch MARCHF3
DgiDB (Drug Gene Interaction Database)MARCHF3
DoCM (Curated mutations)MARCHF3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCHF3 (select a term)
intoGenMARCHF3
Cancer3DMARCHF3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613333   
Orphanet
DisGeNETMARCHF3
MedgenMARCHF3
Genetic Testing Registry MARCHF3
NextProtQ86UD3 [Medical]
GENETestsMARCHF3
Target ValidationMARCHF3
Huge Navigator MARCHF3 [HugePedia]
ClinGenMARCHF3
Clinical trials, drugs, therapy
MyCancerGenomeMARCHF3
Protein Interactions : CTD
Pharm GKB GenePA134901491
Clinical trialMARCHF3
Miscellaneous
canSAR (ICR)MARCHF3 (select the gene name)
HarmonizomeMARCHF3
DataMed IndexMARCHF3
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCHF3
EVEXMARCHF3
GoPubMedMARCHF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:43:30 CET 2020
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