Identity
HGNC
LOCATION
2p11.2
LOCUSID
ALIAS
MATA2,MATII,SAMS2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4144
MIM: 601468
HGNC: 6904
Ensembl: ENSG00000168906
Variants:
dbSNP: 4144
ClinVar: 4144
TCGA: ENSG00000168906
COSMIC: MAT2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168906 | ENST00000306434 | P31153 |
| ENSG00000168906 | ENST00000306434 | A0A140VJP5 |
| ENSG00000168906 | ENST00000409017 | P31153 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37567786 | 2023 | Functional analysis of 3'-UTR hairpins supports a two-tiered model for posttranscriptional regulation of MAT2A by METTL16. | 1 |
| 37567786 | 2023 | Functional analysis of 3'-UTR hairpins supports a two-tiered model for posttranscriptional regulation of MAT2A by METTL16. | 1 |
| 35182729 | 2022 | Activation of MAT2A-ACSL3 pathway protects cells from ferroptosis in gastric cancer. | 14 |
| 35482724 | 2022 | Expression of vimentin, TPI and MAT2A in human dermal microvascular endothelial cells during angiogenesis in vitro. | 2 |
| 35182729 | 2022 | Activation of MAT2A-ACSL3 pathway protects cells from ferroptosis in gastric cancer. | 14 |
| 35482724 | 2022 | Expression of vimentin, TPI and MAT2A in human dermal microvascular endothelial cells during angiogenesis in vitro. | 2 |
| 32492698 | 2021 | Genetic variants in S-adenosyl-methionine synthesis pathway and nonsyndromic cleft lip with or without cleft palate in Chile. | 1 |
| 33450196 | 2021 | MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage. | 64 |
| 33593829 | 2021 | Activation of MAT2A-RIP1 signaling axis reprograms monocytes in gastric cancer. | 15 |
| 33949310 | 2021 | SAM homeostasis is regulated by CFI(m)-mediated splicing of MAT2A. | 18 |
| 34065390 | 2021 | MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients. | 12 |
| 34258296 | 2021 | Circ_0044516 Regulates miR-136/MAT2A Pathway to Facilitate Lung Cancer Development. | 4 |
| 34326469 | 2021 | Genomic and transcriptomic profiling of hepatoid adenocarcinoma of the stomach. | 14 |
| 34610246 | 2021 | MALAT1 Inhibits Proliferation of HPV16-Positive Cervical Cancer by Sponging miR-485-5p to Promote Expression of MAT2A. | 10 |
| 34616406 | 2021 | MAT2A-Mediated S-Adenosylmethionine Level in CD4(+) T Cells Regulates HIV-1 Latent Infection. | 3 |
Citation
Dessen P
MAT2A (methionine adenosyltransferase 2A)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43637/mat2a
