MBD3L2 (methyl-CpG binding domain protein 3 like 2)

2003-06-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 125997
MIM: 607964
HGNC: 18532
Ensembl: ENSG00000230522

Variants:

dbSNP: 125997
ClinVar: 125997
TCGA: ENSG00000230522
COSMIC: MBD3L2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000230522ENST00000381393Q8NHZ7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
267699012016MBD3L2 promotes Tet2 enzymatic activity for mediating 5-methylcytosine oxidation.12
267699012016MBD3L2 promotes Tet2 enzymatic activity for mediating 5-methylcytosine oxidation.12
232398762013Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66α).20
232398762013Unique features of the anti-parallel, heterodimeric coiled-coil interaction between methyl-cytosine binding domain 2 (MBD2) homologues and GATA zinc finger domain containing 2A (GATAD2A/p66α).20
157016002005MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.16
157016002005MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.16

Citation

Dessen P

MBD3L2 (methyl-CpG binding domain protein 3 like 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41311/mbd3l2