Identity
HGNC
LOCATION
3q21.3
LOCUSID
ALIAS
BM28,CCNL1,CDCL1,D3S3194,DFNA70,MITOTIN,cdc19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4171
MIM: 116945
HGNC: 6944
Ensembl: ENSG00000073111
Variants:
dbSNP: 4171
ClinVar: 4171
TCGA: ENSG00000073111
COSMIC: MCM2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38403459 | 2024 | MCM2 is involved in subtyping and tamoxifen resistance of ERα-positive breast cancer by acting as the downstream factor of ERα. | 0 |
| 38454443 | 2024 | Regulation of cancer stem cells by CXCL1, a chemokine whose secretion is controlled by MCM2. | 0 |
| 38403459 | 2024 | MCM2 is involved in subtyping and tamoxifen resistance of ERα-positive breast cancer by acting as the downstream factor of ERα. | 0 |
| 38454443 | 2024 | Regulation of cancer stem cells by CXCL1, a chemokine whose secretion is controlled by MCM2. | 0 |
| 36778110 | 2023 | ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway. | 2 |
| 36807739 | 2023 | The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress. | 1 |
| 37358551 | 2023 | Circ_0104700 contributes to acute myeloid leukemia progression by enhancing MCM2 expression through targeting miR-665. | 1 |
| 38053378 | 2023 | MCM2 promotes the stemness of endometrial cancer cells via the Akt/β-catenin pathway. | 0 |
| 36778110 | 2023 | ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway. | 2 |
| 36807739 | 2023 | The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress. | 1 |
| 37358551 | 2023 | Circ_0104700 contributes to acute myeloid leukemia progression by enhancing MCM2 expression through targeting miR-665. | 1 |
| 38053378 | 2023 | MCM2 promotes the stemness of endometrial cancer cells via the Akt/β-catenin pathway. | 0 |
| 35093119 | 2022 | Demethylation at enhancer upregulates MCM2 and NUP37 expression predicting poor survival in hepatocellular carcinoma patients. | 10 |
| 35307646 | 2022 | MCM2 promotes the proliferation, migration and invasion of cholangiocarcinoma cells by reducing the p53 signaling pathway. | 2 |
| 35438632 | 2022 | MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells. | 13 |
Citation
Dessen P
MCM2 (minichromosome maintenance complex component 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/41318/mcm2
