Identity
HGNC
LOCATION
2q21.3
LOCUSID
ALIAS
MCG40308,Mis5,P105MCM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4175
MIM: 601806
HGNC: 6949
Ensembl: ENSG00000076003
Variants:
dbSNP: 4175
ClinVar: 4175
TCGA: ENSG00000076003
COSMIC: MCM6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000076003 | ENST00000264156 | Q14566 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37119503 | 2024 | Hypoxia Induces Tumor-Derived Exosome SNHG16 to Mediate Nasopharyngeal Carcinoma Progression through the miR-23b-5p/MCM6 Pathway. | 0 |
| 38347378 | 2024 | MCM6 Inhibits Decidualization via Cross-Talking with ERK Pathway in Human Endometrial Stromal Cells. | 0 |
| 38639528 | 2024 | High MCM6 expression promotes proliferation and correlates with poor prognosis in triple-negative breast cancer. | 0 |
| 38773180 | 2024 | In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene. | 0 |
| 37119503 | 2024 | Hypoxia Induces Tumor-Derived Exosome SNHG16 to Mediate Nasopharyngeal Carcinoma Progression through the miR-23b-5p/MCM6 Pathway. | 0 |
| 38347378 | 2024 | MCM6 Inhibits Decidualization via Cross-Talking with ERK Pathway in Human Endometrial Stromal Cells. | 0 |
| 38639528 | 2024 | High MCM6 expression promotes proliferation and correlates with poor prognosis in triple-negative breast cancer. | 0 |
| 38773180 | 2024 | In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene. | 0 |
| 37185675 | 2023 | MCM6 promotes intrahepatic cholangiocarcinoma progression by upregulating E2F1 and enhancing epithelial-mesenchymal transition. | 1 |
| 37198333 | 2023 | De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues. | 0 |
| 37454373 | 2023 | UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells. | 0 |
| 37185675 | 2023 | MCM6 promotes intrahepatic cholangiocarcinoma progression by upregulating E2F1 and enhancing epithelial-mesenchymal transition. | 1 |
| 37198333 | 2023 | De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues. | 0 |
| 37454373 | 2023 | UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells. | 0 |
| 36185598 | 2022 | MCM6 is a critical transcriptional target of YAP to promote gastric tumorigenesis and serves as a therapeutic target. | 6 |
Citation
Dessen P
MCM6 (minichromosome maintenance complex component 6)
Atlas Genet Cytogenet Oncol Haematol. 2003-08-01
Online version: http://atlasgeneticsoncology.org/gene/41322/mcm6
