Identity
HGNC
LOCATION
20p12.3
LOCUSID
ALIAS
C20orf154,POF10,dJ967N21.5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84515
MIM: 608187
HGNC: 16147
Ensembl: ENSG00000125885
Variants:
dbSNP: 84515
ClinVar: 84515
TCGA: ENSG00000125885
COSMIC: MCM8
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38588931 | 2024 | A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8. | 0 |
| 38678026 | 2024 | Mechanism of DNA unwinding by MCM8-9 in complex with HROB. | 1 |
| 38588931 | 2024 | A novel cancer-germline gene DAZL promotes progression and cisplatin resistance of non-small cell lung cancer by upregulating JAK2 and MCM8. | 0 |
| 38678026 | 2024 | Mechanism of DNA unwinding by MCM8-9 in complex with HROB. | 1 |
| 37309874 | 2023 | Activity, substrate preference and structure of the HsMCM8/9 helicase. | 1 |
| 37349788 | 2023 | Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics. | 0 |
| 37309874 | 2023 | Activity, substrate preference and structure of the HsMCM8/9 helicase. | 1 |
| 37349788 | 2023 | Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics. | 0 |
| 34889489 | 2022 | Associations of MCM8 rs3761873 and rs16991617 variants with abnormal uterine bleeding induced by copper intrauterine device. | 1 |
| 34889489 | 2022 | Associations of MCM8 rs3761873 and rs16991617 variants with abnormal uterine bleeding induced by copper intrauterine device. | 1 |
| 33828075 | 2021 | Knockdown of MCM8 functions as a strategy to inhibit the development and progression of osteosarcoma through regulating CTGF. | 7 |
| 34043945 | 2021 | Structural study of the N-terminal domain of human MCM8/9 complex. | 6 |
| 34131285 | 2021 | MCM8 is regulated by EGFR signaling and promotes the growth of glioma stem cells through its interaction with DNA-replication-initiating factors. | 14 |
| 33828075 | 2021 | Knockdown of MCM8 functions as a strategy to inhibit the development and progression of osteosarcoma through regulating CTGF. | 7 |
| 34043945 | 2021 | Structural study of the N-terminal domain of human MCM8/9 complex. | 6 |
Citation
Dessen P
MCM8 (minichromosome maintenance 8 homologous recombination repair factor)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43359/mcm8
