MCTS1 (MCTS1 re-initiation and release factor)

2003-02-01  

Identity

HGNC
LOCATION
Xq24
LOCUSID
ALIAS
MCT-1,MCT1

Other Information

Locus ID:

NCBI: 28985
MIM: 300587
HGNC: 23357
Ensembl: ENSG00000232119

Variants:

dbSNP: 28985
ClinVar: 28985
TCGA: ENSG00000232119
COSMIC: MCTS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000232119ENST00000371315Q9ULC4
ENSG00000232119ENST00000371317Q9ULC4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

References

Pubmed IDYearTitleCitations
232588462013Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets.78
206581782010Co-expression of CD147/EMMPRIN with monocarboxylate transporters and multiple drug resistance proteins is associated with epithelial ovarian cancer progression.31
308852322019MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer.25
287325962017Structural and Functional Insights into Human Re-initiation Complexes.18
126373152003Expression of the candidate MCT-1 oncogene in B- and T-cell lymphoid malignancies.14
287235572017Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.13
287235572017Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.13
193725822009Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity.11
188242612009Targeted suppression of MCT-1 attenuates the malignant phenotype through a translational mechanism.9
211385572010The antagonism between MCT-1 and p53 affects the tumorigenic outcomes.6

Citation

Dessen P

MCTS1 (MCTS1 re-initiation and release factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41324/mcts1