MDFIC (MyoD family inhibitor domain containing)

2014-11-01  

Identity

HGNC
LOCATION
7q31.1
LOCUSID
ALIAS
HIC,MDFIC1

Other Information

Locus ID:

NCBI: 29969
MIM: 614511
HGNC: 28870
Ensembl: ENSG00000135272

Variants:

dbSNP: 29969
ClinVar: 29969
TCGA: ENSG00000135272
COSMIC: MDFIC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135272ENST00000257724J3KN13
ENSG00000135272ENST00000393486Q9P1T7
ENSG00000135272ENST00000423503C9J104
ENSG00000135272ENST00000427207H7BZY3
ENSG00000135272ENST00000431629H7C4B9
ENSG00000135272ENST00000448022C9J104
ENSG00000135272ENST00000498196C9J784

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
106715202000Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expression.18
204176162010Human I-mfa domain proteins specifically interact with KSHV LANA and affect its regulation of Wnt signaling-dependent transcription.13
214019182011Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import.10
264695492015I-mfa domain proteins specifically interact with HTLV-1 Tax and repress its transactivating functions.8
282233522017Cross-talk between the glucocorticoid receptor and MyoD family inhibitor domain-containing protein provides a new mechanism for generating tissue-specific responses to glucocorticoids.8
194285672009Expression profile and differential regulation of the Human I-mfa domain-Containing protein (HIC) gene in immune cells.4
195821492009The complex regulation of HIC (Human I-mfa domain containing protein) expression.2

Citation

Dessen P

MDFIC (MyoD family inhibitor domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68859/mdfic