MEAF6 (MYST/Esa1 associated factor 6)

2005-02-01  

Identity

HGNC
MEAF6
LOCATION
1p34.3
LOCUSID
64769
ALIAS
C1orf149,CENP-28,EAF6,NY-SAR-91
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64769
MIM: 611001
HGNC: 25674
Ensembl: ENSG00000163875

Variants:

dbSNP: 64769
ClinVar: 64769
TCGA: ENSG00000163875
COSMIC: MEAF6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163875ENST00000296214Q9HAF1
ENSG00000163875ENST00000373073Q9HAF1
ENSG00000163875ENST00000373074B1AK63
ENSG00000163875ENST00000373075Q9HAF1
ENSG00000163875ENST00000448519Q9HAF1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through AcetylationREACTOMER-HSA-6804758

References

Pubmed IDYearTitleCitations
350746162022MiR-197-3p reduces bortezomib resistance in multiple myeloma by inhibiting IL-6 expression in a MEAF6-dependent manner.5
350746162022MiR-197-3p reduces bortezomib resistance in multiple myeloma by inhibiting IL-6 expression in a MEAF6-dependent manner.5
284271942017Alternative RNA splicing of the MEAF6 gene facilitates neuroendocrine prostate cancer progression.16
284271942017Alternative RNA splicing of the MEAF6 gene facilitates neuroendocrine prostate cancer progression.16
242854342014Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma.51
245302302014MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma.27
242854342014Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma.51
245302302014MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma.27

Citation

Dessen P

MEAF6 (MYST/Esa1 associated factor 6)

Atlas Genet Cytogenet Oncol Haematol. 2005-02-01

Online version: http://atlasgeneticsoncology.org/gene/45510/meaf6