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MEAK7 (MTOR associated protein, eak-7 homolog)

Identity

Alias_namesKIAA1609
TLDC1
KIAA1609
TBC/LysM-associated domain containing 1
Alias_symbol (synonym)mEAK-7
Other alias
HGNC (Hugo) MEAK7
LocusID (NCBI) 57707
Atlas_Id 57864
Location 16q24.1  [Link to chromosome band 16q24]
Location_base_pair Starts at 84476360 and ends at 84504682 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)MEAK7   29325
Cards
Entrez_Gene (NCBI)MEAK7  57707  MTOR associated protein, eak-7 homolog
AliasesKIAA1609; TLDC1; mEAK-7
GeneCards (Weizmann)MEAK7
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr16:84476360-84504682 [Contig_View]  MEAK7 [Vega]
TCGA cBioPortalMEAK7
AceView (NCBI)MEAK7
Genatlas (Paris)MEAK7
WikiGenes57707
SOURCE (Princeton)MEAK7
Genetics Home Reference (NIH)MEAK7
Genomic and cartography
GoldenPath hg38 (UCSC)MEAK7  -     chr16:84476360-84504682 -  16q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MEAK7  -     16q24.1   [Description]    (hg19-Feb_2009)
GoldenPathMEAK7 - 16q24.1 [CytoView hg19]  MEAK7 - 16q24.1 [CytoView hg38]
Mapping of homologs : NCBIMEAK7 [Mapview hg19]  MEAK7 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA115393 AB046829 AK021995 AK291237 AK297241
RefSeq transcript (Entrez)NM_020947
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MEAK7
Cluster EST : UnigeneHs.288274 [ NCBI ]
CGAP (NCI)Hs.288274
Gene ExpressionMEAK7 [ NCBI-GEO ]   MEAK7 [ EBI - ARRAY_EXPRESS ]   MEAK7 [ SEEK ]   MEAK7 [ MEM ]
Gene Expression Viewer (FireBrowse)MEAK7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57707
GTEX Portal (Tissue expression)MEAK7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P9B6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P9B6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P9B6
Splice isoforms : SwissVarQ6P9B6
PhosPhoSitePlusQ6P9B6
Domains : Interpro (EBI)TLDc_dom   
Domain families : Pfam (Sanger)TLD (PF07534)   
Domain families : Pfam (NCBI)pfam07534   
Domain families : Smart (EMBL)TLDc (SM00584)  
Conserved Domain (NCBI)MEAK7
DMDM Disease mutations57707
Blocks (Seattle)MEAK7
SuperfamilyQ6P9B6
Peptide AtlasQ6P9B6
IPIIPI00412243   IPI01010000   IPI01012247   IPI00979347   
Protein Interaction databases
DIP (DOE-UCLA)Q6P9B6
IntAct (EBI)Q6P9B6
BioGRIDMEAK7
STRING (EMBL)MEAK7
ZODIACMEAK7
Ontologies - Pathways
QuickGOQ6P9B6
Ontology : AmiGOprotein binding  cytoplasm  lysosomal membrane  lysosomal membrane  membrane  regulation of cell migration  response to nutrient levels  TOR signaling  response to insulin  regulation of cell proliferation  response to amino acid  positive regulation of protein localization to lysosome  negative regulation of oxidative stress-induced neuron death  
Ontology : EGO-EBIprotein binding  cytoplasm  lysosomal membrane  lysosomal membrane  membrane  regulation of cell migration  response to nutrient levels  TOR signaling  response to insulin  regulation of cell proliferation  response to amino acid  positive regulation of protein localization to lysosome  negative regulation of oxidative stress-induced neuron death  
NDEx NetworkMEAK7
Atlas of Cancer Signalling NetworkMEAK7
Wikipedia pathwaysMEAK7
Orthology - Evolution
OrthoDB57707
Phylogenetic Trees/Animal Genes : TreeFamMEAK7
HOGENOMQ6P9B6
Homologs : HomoloGeneMEAK7
Homology/Alignments : Family Browser (UCSC)MEAK7
Gene fusions - Rearrangements
Fusion : QuiverMEAK7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMEAK7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MEAK7
dbVarMEAK7
ClinVarMEAK7
1000_GenomesMEAK7 
Exome Variant ServerMEAK7
Varsome BrowserMEAK7
Genetic variants : HAPMAP57707
Genomic Variants (DGV)MEAK7 [DGVbeta]
DECIPHERMEAK7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMEAK7 
Mutations
ICGC Data PortalMEAK7 
TCGA Data PortalMEAK7 
Broad Tumor PortalMEAK7
OASIS PortalMEAK7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMEAK7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMEAK7
Mutations and Diseases : HGMDMEAK7
BioMutasearch MEAK7
DgiDB (Drug Gene Interaction Database)MEAK7
DoCM (Curated mutations)MEAK7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MEAK7 (select a term)
intoGenMEAK7
Cancer3DMEAK7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETMEAK7
MedgenMEAK7
Genetic Testing Registry MEAK7
NextProtQ6P9B6 [Medical]
TSGene57707
GENETestsMEAK7
Target ValidationMEAK7
Huge Navigator MEAK7 [HugePedia]
snp3D : Map Gene to Disease57707
BioCentury BCIQMEAK7
ClinGenMEAK7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57707
Chemical/Pharm GKB GenePA144596416
Clinical trialMEAK7
Miscellaneous
canSAR (ICR)MEAK7 (select the gene name)
DataMed IndexMEAK7
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMEAK7
EVEXMEAK7
GoPubMedMEAK7
iHOPMEAK7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:53:05 CET 2019

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