Identity
HGNC
LOCATION
17q12
LOCUSID
ALIAS
CRSP1,CRSP200,DRIP205,DRIP230,PBP,PPARBP,PPARGBP,RB18A,TRAP220,TRIP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5469
MIM: 604311
HGNC: 9234
Ensembl: ENSG00000125686
Variants:
dbSNP: 5469
ClinVar: 5469
TCGA: ENSG00000125686
COSMIC: MED1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125686 | ENST00000300651 | Q15648 |
| ENSG00000125686 | ENST00000394287 | Q15648 |
| ENSG00000125686 | ENST00000577831 | J3QKZ7 |
| ENSG00000125686 | ENST00000581334 | J3KSD7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38428427 | 2024 | Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation. | 0 |
| 38428427 | 2024 | Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation. | 0 |
| 36191835 | 2023 | Mediator subunit MED1 differentially modulates mutant thyroid hormone receptor intracellular dynamics in Resistance to Thyroid Hormone syndrome. | 0 |
| 37594664 | 2023 | MED1 induces M2 polarization of tumor-associated macrophages to aggravate breast cancer. | 0 |
| 37668531 | 2023 | Mediator subunit MED1 deficiency prevents carbon tetrachloride-induced hepatic fibrosis in mice. | 1 |
| 36191835 | 2023 | Mediator subunit MED1 differentially modulates mutant thyroid hormone receptor intracellular dynamics in Resistance to Thyroid Hormone syndrome. | 0 |
| 37594664 | 2023 | MED1 induces M2 polarization of tumor-associated macrophages to aggravate breast cancer. | 0 |
| 37668531 | 2023 | Mediator subunit MED1 deficiency prevents carbon tetrachloride-induced hepatic fibrosis in mice. | 1 |
| 35131256 | 2022 | MED1 Downregulation Contributes to TGFβ-Induced Metastasis by Inhibiting SMAD2 Ubiquitination Degradation in Cutaneous Melanoma. | 4 |
| 35394046 | 2022 | Phosphorylated MED1 links transcription recycling and cancer growth. | 2 |
| 35512686 | 2022 | Targeting cyclin-dependent kinase 7-association between CDK7 and pMED1 expression in prostate cancer tissue. | 3 |
| 35916453 | 2022 | Overexpression of circFNDC3B promotes the progression of oral tongue squamous cell carcinoma through the miR-1322/MED1 axis. | 1 |
| 35131256 | 2022 | MED1 Downregulation Contributes to TGFβ-Induced Metastasis by Inhibiting SMAD2 Ubiquitination Degradation in Cutaneous Melanoma. | 4 |
| 35394046 | 2022 | Phosphorylated MED1 links transcription recycling and cancer growth. | 2 |
| 35512686 | 2022 | Targeting cyclin-dependent kinase 7-association between CDK7 and pMED1 expression in prostate cancer tissue. | 3 |
Citation
Dessen P
MED1 (mediator complex subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/185/med1
