MED20 (mediator complex subunit 20)

2014-11-01  

Identity

HGNC
MED20
LOCATION
6p21.1
LOCUSID
9477
ALIAS
PRO0213,SRB2,TRFP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9477
MIM: 612915
HGNC: 16840
Ensembl: ENSG00000124641

Variants:

dbSNP: 9477
ClinVar: 9477
TCGA: ENSG00000124641
COSMIC: MED20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124641ENST00000265350Q9H944
ENSG00000124641ENST00000394251A6PVP4
ENSG00000124641ENST00000409060B7ZBQ3
ENSG00000124641ENST00000409312Q9H944
ENSG00000124641ENST00000434077B7ZBQ1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of white adipocyte differentiationREACTOMER-HSA-381340

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
289471012017All three human scavenger receptor class B proteins can bind and transport all three macular xanthophyll carotenoids.11
254464062015MED20 mutation associated with infantile basal ganglia degeneration and brain atrophy.0

Citation

Dessen P

MED20 (mediator complex subunit 20)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68876/med20