MEIOB (meiosis specific with OB-fold)

2013-12-01 Affiliation

Identity

HGNC

MEIOB

LOCATION

16p13.3

LOCUSID

254528

ALIAS

C16orf73,SPGF22,gs129

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 254528
MIM: 617670
HGNC: 28569
Ensembl: ENSG00000162039

Variants:

dbSNP: 254528
ClinVar: 254528
TCGA: ENSG00000162039
COSMIC: MEIOB

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000162039	ENST00000325962	Q8N635
ENSG00000162039	ENST00000397344	Q8N635
ENSG00000162039	ENST00000460494	H3BU18
ENSG00000162039	ENST00000470044	H3BU10
ENSG00000162039	ENST00000496541	H3BSU6

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
24068956	2013	MEIOB targets single-strand DNA and is necessary for meiotic recombination.	0
24240703	2013	MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination.	0
31000419	2019	A truncating MEIOB mutation responsible for familial primary ovarian insufficiency abolishes its interaction with its partner SPATA22 and their recruitment to DNA double-strand breaks.	0

Citation

Dessen P

MEIOB (meiosis specific with OB-fold)

Atlas Genet Cytogenet Oncol Haematol. 2013-12-01

Online version: http://atlasgeneticsoncology.org/gene/53635/meiob