Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4225
MIM: 600389
HGNC: 7020
Ensembl: ENSG00000141434
Variants:
dbSNP: 4225
ClinVar: 4225
TCGA: ENSG00000141434
COSMIC: MEP1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000141434 | ENST00000269202 | Q16820 |
| ENSG00000141434 | ENST00000581184 | J3KRK1 |
| ENSG00000141434 | ENST00000581447 | J3QKX5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein digestion and absorption | KEGG | ko04974 |
| Protein digestion and absorption | KEGG | hsa04974 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36976399 | 2023 | The putative pleiotropic functions of meprin β in gastric cancer. | 0 |
| 36976399 | 2023 | The putative pleiotropic functions of meprin β in gastric cancer. | 0 |
| 34073350 | 2021 | Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor. | 2 |
| 34073350 | 2021 | Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor. | 2 |
| 31076514 | 2019 | The cancer-associated meprin β variant G32R provides an additional activation site and promotes cancer cell invasion. | 7 |
| 31604820 | 2019 | Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β. | 0 |
| 31076514 | 2019 | The cancer-associated meprin β variant G32R provides an additional activation site and promotes cancer cell invasion. | 7 |
| 31604820 | 2019 | Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β. | 0 |
| 28059112 | 2017 | Meprin β contributes to collagen deposition in lung fibrosis. | 17 |
| 28365001 | 2017 | Meprin β and BMP-1 are differentially regulated by CaCl(2). | 1 |
| 28502593 | 2017 | Meprin metalloproteases: Molecular regulation and function in inflammation and fibrosis. | 19 |
| 29166602 | 2017 | Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB. | 16 |
| 28059112 | 2017 | Meprin β contributes to collagen deposition in lung fibrosis. | 17 |
| 28365001 | 2017 | Meprin β and BMP-1 are differentially regulated by CaCl(2). | 1 |
| 28502593 | 2017 | Meprin metalloproteases: Molecular regulation and function in inflammation and fibrosis. | 19 |
Citation
Dessen P
MEP1B (meprin A subunit beta)
Atlas Genet Cytogenet Oncol Haematol. 2003-10-01
Online version: http://atlasgeneticsoncology.org/gene/41336/mep1b
