MEX3B (mex-3 RNA binding family member B)

2007-04-01  

Identity

HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
MEX-3B,RKHD3,RNF195

Other Information

Locus ID:

NCBI: 84206
MIM: 611008
HGNC: 25297
Ensembl: ENSG00000183496

Variants:

dbSNP: 84206
ClinVar: 84206
TCGA: ENSG00000183496
COSMIC: MEX3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183496ENST00000329713Q6ZN04
ENSG00000183496ENST00000558133Q6ZN04

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383264062024Molecular mechanism of specific HLA-A mRNA recognition by the RNA-binding-protein hMEX3B to promote tumor immune escape.0
383264062024Molecular mechanism of specific HLA-A mRNA recognition by the RNA-binding-protein hMEX3B to promote tumor immune escape.0
369766452023MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability.0
369766452023MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability.0
313302192020The IL-37-Mex3B-Toll-like receptor 3 axis in epithelial cells in patients with eosinophilic chronic rhinosinusitis with nasal polyps.12
313302192020The IL-37-Mex3B-Toll-like receptor 3 axis in epithelial cells in patients with eosinophilic chronic rhinosinusitis with nasal polyps.12
294172972018HOTAIR induces the ubiquitination of Runx3 by interacting with Mex3b and enhances the invasion of gastric cancer cells.40
294967592018The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.53
294172972018HOTAIR induces the ubiquitination of Runx3 by interacting with Mex3b and enhances the invasion of gastric cancer cells.40
294967592018The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.53
187793272008Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.25
187793272008Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.25

Citation

Dessen P

MEX3B (mex-3 RNA binding family member B)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47358/mex3b