Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8076
MIM: 601103
HGNC: 29673
Ensembl: ENSG00000197614
Variants:
dbSNP: 8076
ClinVar: 8076
TCGA: ENSG00000197614
COSMIC: MFAP5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Extracellular matrix organization | REACTOME | R-HSA-1474244 |
| Elastic fibre formation | REACTOME | R-HSA-1566948 |
| Molecules associated with elastic fibres | REACTOME | R-HSA-2129379 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36934797 | 2023 | Microfibril-Associated Glycoprotein-2 Promoted Fracture Healing via Integrin αvβ3/PTK2/AKT Signaling. | 1 |
| 37156839 | 2023 | Targeting MFAP5 in cancer-associated fibroblasts sensitizes pancreatic cancer to PD-L1-based immunochemotherapy via remodeling the matrix. | 7 |
| 36934797 | 2023 | Microfibril-Associated Glycoprotein-2 Promoted Fracture Healing via Integrin αvβ3/PTK2/AKT Signaling. | 1 |
| 37156839 | 2023 | Targeting MFAP5 in cancer-associated fibroblasts sensitizes pancreatic cancer to PD-L1-based immunochemotherapy via remodeling the matrix. | 7 |
| 34915136 | 2022 | MAGP2 induces tumor progression by enhancing uPAR-mediated cell proliferation. | 2 |
| 34915136 | 2022 | MAGP2 induces tumor progression by enhancing uPAR-mediated cell proliferation. | 2 |
| 32895766 | 2021 | Reduced MFAP5 expression in stroma of gallbladder adenocarcinoma and its potential diagnostic utility. | 0 |
| 32895766 | 2021 | Reduced MFAP5 expression in stroma of gallbladder adenocarcinoma and its potential diagnostic utility. | 0 |
| 31190277 | 2020 | Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling. | 14 |
| 31422503 | 2020 | Loss of microfibril-associated protein 5 (MFAP5) expression in colon cancer stroma. | 5 |
| 32293074 | 2020 | CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling. | 18 |
| 31190277 | 2020 | Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling. | 14 |
| 31422503 | 2020 | Loss of microfibril-associated protein 5 (MFAP5) expression in colon cancer stroma. | 5 |
| 32293074 | 2020 | CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling. | 18 |
| 30320661 | 2019 | Immunohistochemical Expression of Microfibrillar-associated Protein 5 (MFAP5) in Invasive Breast Carcinoma of No Special Type. | 1 |
Citation
Dessen P
MFAP5 (microfibril associated protein 5)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51289/mfap5
