MFHAS1 (multifunctional ROCO family signaling regulator 1)

2003-02-01  

Identity

HGNC
LOCATION
8p23.1
LOCUSID
ALIAS
LRRC65,MASL1,ROCO4
FUSION GENES

Other Information

Locus ID:

NCBI: 9258
MIM: 605352
HGNC: 16982
Ensembl: ENSG00000147324

Variants:

dbSNP: 9258
ClinVar: 9258
TCGA: ENSG00000147324
COSMIC: MFHAS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147324ENST00000276282Q9Y4C4

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
206160632011Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
207340642010A large-scale candidate gene association study of age at menarche and age at natural menopause.38
233279232013MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway.14
146914502004MASL1, a candidate oncogene found in amplification at 8p23.1, is translocated in immunoblastic B-cell lymphoma cell line OCI-LY8.8
229888712012MASL1: a neglected ROCO protein.8
286097142017MFHAS1 suppresses TLR4 signaling pathway via induction of PP2A C subunit cytoplasm translocation and inhibition of c-Jun dephosphorylation at Thr239.4
291680812018High Glucose Stimulates Expression of MFHAS1 to Mitigate Inflammation via Akt/HO-1 Pathway in Human Umbilical Vein Endothelial Cells.2

Citation

Dessen P

MFHAS1 (multifunctional ROCO family signaling regulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41343/mfhas1