MIR10A (microRNA 10a)

2009-03-01  

Identity

HGNC
MIR10A
LOCATION
17q21.32
LOCUSID
406902
ALIAS
MIRN10A,hsa-mir-10a,miRNA10A,mir-10a

Other Information

Locus ID:

NCBI: 406902
MIM: 610173
HGNC: 31497
Ensembl: ENSG00000284038
miRBase:

Variants:

dbSNP: 406902
ClinVar: 406902
TCGA: ENSG00000284038
COSMIC: MIR10A

RNA/Proteins

Pathways

PathwaySourceExternal ID
Proteoglycans in cancerKEGGhsa05205
Proteoglycans in cancerKEGGko05205
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Fluid shear stress and atherosclerosisKEGGko05418
Fluid shear stress and atherosclerosisKEGGhsa05418

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA33308PIK3CAGeneLiterature, MultilinkAnnotationassociated24522205

References

Pubmed IDYearTitleCitations
190748282008Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth.79
263175522015MiRNA-10a is upregulated in NSCLC and may promote cancer by targeting PTEN.54
226344952012MicroRNA-10a targets CHL1 and promotes cell growth, migration and invasion in human cervical cancer cells.47
224073122012MicroRNA-10a is overexpressed in human pancreatic cancer and involved in its invasiveness partially via suppression of the HOXA1 gene.43
236853552013Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma.35
229557332012MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling.28
256830042015miR-10a controls glioma migration and invasion through regulating epithelial-mesenchymal transition via EphA8.21
217840522011miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia.19
236964172013miR-10a restores human mesenchymal stem cell differentiation by repressing KLF4.18
255867402015MicroRNA-10a silencing reverses cisplatin resistance in the A549/cisplatin human lung cancer cell line via the transforming growth factor-β/Smad2/STAT3/STAT5 pathway.17

Citation

Dessen P

MIR10A (microRNA 10a)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50689/mir10a