MIR128-2 (microRNA 128-2)

2011-09-01  

Identity

HGNC
LOCATION
3p22.3
LOCUSID
ALIAS
MIR128B,MIRN128-2,MIRN128B,mir-128-2,mir-128b

Other Information

Locus ID:

NCBI: 406916
MIM: 611769
HGNC: 31511
Ensembl: ENSG00000207625
miRBase:

Variants:

dbSNP: 406916
ClinVar: 406916
TCGA: ENSG00000207625
COSMIC: MIR128-2

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
221935432012MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function.59
197135292009MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness.56
286275142017Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC.35
257049212015Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma.29
264609602015MicroRNA-27b, microRNA-101 and microRNA-128 inhibit angiogenesis by down-regulating vascular endothelial growth factor C expression in gastric cancers.29
300764142019Long noncoding RNA PVT1-214 promotes proliferation and invasion of colorectal cancer by stabilizing Lin28 and interacting with miR-128.29
239900202013Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis.28
249599302014An axis involving SNAI1, microRNA-128 and SP1 modulates glioma progression.19
248598862014Loss of SNAIL inhibits cellular growth and metabolism through the miR-128-mediated RPS6KB1/HIF-1α/PKM2 signaling pathway in prostate cancer cells.16
281793592017VEGFA activates an epigenetic pathway upregulating ovarian cancer-initiating cells.13

Citation

Dessen P

MIR128-2 (microRNA 128-2)

Atlas Genet Cytogenet Oncol Haematol. 2011-09-01

Online version: http://atlasgeneticsoncology.org/gene/52376/mir128-2