MIR130A (microRNA 130a)

2010-12-01  

Identity

HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
MIRN130A,miRNA130A,mir-130a

Other Information

Locus ID:

NCBI: 406919
MIM: 610175
HGNC: 31514
Ensembl: ENSG00000208009
miRBase:

Variants:

dbSNP: 406919
ClinVar: 406919
TCGA: ENSG00000208009
COSMIC: MIR130A

RNA/Proteins

References

Pubmed IDYearTitleCitations
211351282011miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression.114
249538322014Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer.82
217060502012miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222.74
223504152012miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells.63
227872042012Hepatitis C virus infection modulates expression of interferon stimulatory gene IFITM1 by upregulating miR-130A.53
228465642012Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell.50
226148692012Altered microRNA expression in cisplatin-resistant ovarian cancer cells and upregulation of miR-130a associated with MDR1/P-glycoprotein-mediated drug resistance.40
264369202015miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.40
262721682015A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis.34
260334532015Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients.33

Citation

Dessen P

MIR130A (microRNA 130a)

Atlas Genet Cytogenet Oncol Haematol. 2010-12-01

Online version: http://atlasgeneticsoncology.org/gene/51831/mir130a