MIR140 (microRNA 140)

2013-02-01  

Identity

HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
MIRN140,SEDN,miRNA140,mir-140

Other Information

Locus ID:

NCBI: 406932
MIM: 611894
HGNC: 31527
Ensembl: ENSG00000208017
miRBase:

Variants:

dbSNP: 406932
ClinVar: 406932
TCGA: ENSG00000208017
COSMIC: MIR140

RNA/Proteins

References

Pubmed IDYearTitleCitations
197145792009MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses.121
199480512009Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.74
275977392016Long non-coding RNA Unigene56159 promotes epithelial-mesenchymal transition by acting as a ceRNA of miR-140-5p in hepatocellular carcinoma cells.49
230604402012Estrogen receptor α signaling regulates breast tumor-initiating cells by down-regulating miR-140 which targets the transcription factor SOX2.46
199502262010Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women.45
259804952015Inhibition of colorectal cancer stem cell survival and invasive potential by hsa-miR-140-5p mediated suppression of Smad2 and autophagy.42
272145542016MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.37
288181002017miR-140-5p suppresses the proliferation, migration and invasion of gastric cancer by regulating YES1.37
227736912012miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells.36
228989982013MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression.36

Citation

Dessen P

MIR140 (microRNA 140)

Atlas Genet Cytogenet Oncol Haematol. 2013-02-01

Online version: http://atlasgeneticsoncology.org/gene/53184/mir140