MIR181A1 (microRNA 181a-1)

2010-10-01  

Identity

HGNC
LOCATION
1q32.1
LOCUSID
ALIAS
MIR213,MIRN181A1,MIRN213,hsa-mir-181a-1,mir-181a-1,mir-213

Other Information

Locus ID:

NCBI: 406995
MIM: 612742
HGNC: 31590
Ensembl: ENSG00000207759
miRBase:

Variants:

dbSNP: 406995
ClinVar: 406995
TCGA: ENSG00000207759
COSMIC: MIR181A1

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
211025232011Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM.109
222514802012Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.75
211671322011miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras.71
247552952014MicroRNA-181a promotes tumor growth and liver metastasis in colorectal cancer by targeting the tumor suppressor WIF-1.43
283888832017Long non-coding RNA XIST regulates PTEN expression by sponging miR-181a and promotes hepatocellular carcinoma progression.36
239117472013MicroRNA-181a suppresses salivary adenoid cystic carcinoma metastasis by targeting MAPK-Snai2 pathway.34
192735992009miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cells.31
229865342013Interleukin enhancer-binding factor 3 promotes breast tumor progression by regulating sustained urokinase-type plasminogen activator expression.30
211598452011Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC).29
231003112013Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.29

Citation

Dessen P

MIR181A1 (microRNA 181a-1)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51691/mir181a1