MIR181B1 (microRNA 181b-1)

2010-10-01  

Identity

HGNC
MIR181B1
LOCATION
1q32.1
LOCUSID
406955
ALIAS
MIRN181B1,mir-181b-1

Other Information

Locus ID:

NCBI: 406955
MIM: 612744
HGNC: 31550
Ensembl: ENSG00000207975
miRBase:

Variants:

dbSNP: 406955
ClinVar: 406955
TCGA: ENSG00000207975
COSMIC: MIR181B1

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
207976232010STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer.333
222514802012Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.75
253474722014Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.49
224463322012miR-181b promotes hepatic stellate cells proliferation by targeting p27 and is elevated in the serum of cirrhosis patients.39
203472652010MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia.34
234314082013MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas.33
225815222012MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6.29
247561632014miR-181b increases drug sensitivity in acute myeloid leukemia via targeting HMGB1 and Mcl-1.29
242696842014miR-181b promotes cell proliferation and reduces apoptosis by repressing the expression of adenylyl cyclase 9 (AC9) in cervical cancer cells.24
255352552015Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis.23

Citation

Dessen P

MIR181B1 (microRNA 181b-1)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51711/mir181b1