MIR199A1 (microRNA 199a-1)

2008-09-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
MIR-199-s,MIRN199A1,mir-199a-1

Other Information

Locus ID:

NCBI: 406976
MIM: 610719
HGNC: 31571
Ensembl: ENSG00000207752
miRBase:

Variants:

dbSNP: 406976
ClinVar: 406976
TCGA: ENSG00000207752
COSMIC: MIR199A1

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
184087582008Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells.126
184566602008MicroRNA miR-199a* regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2).92
210553882010miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines.62
230857572013miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.57
213836892011Methylation of an intronic region regulates miR-199a in testicular tumor malignancy.55
248103362014miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma.49
211893272011MicroRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers.48
280733802017Long non-coding RNA small nucleolar RNA host gene 12 (SNHG12) promotes tumorigenesis and metastasis by targeting miR-199a/b-5p in hepatocellular carcinoma.44
250809372014SRF expedites metastasis and modulates the epithelial to mesenchymal transition by regulating miR-199a-5p expression in human gastric cancer.41
283583692017MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2.39

Citation

Dessen P

MIR199A1 (microRNA 199a-1)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50334/mir199a1