MIR25 (microRNA 25)

2008-04-01  

Identity

HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
MIRN25,hsa-mir-25,miR-25

Other Information

Locus ID:

NCBI: 407014
MIM: 612150
HGNC: 31609
Ensembl: ENSG00000207547
miRBase:

Variants:

dbSNP: 407014
ClinVar: 407014
TCGA: ENSG00000207547
COSMIC: MIR25

RNA/Proteins

Expression (GTEx)

0
1
2

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
183284302008E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer.348
203889162010Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.185
209356782011Negative regulation of the tumor suppressor p53 gene by microRNAs.105
219530562012miR-25 targets TNF-related apoptosis inducing ligand (TRAIL) death receptor-4 and promotes apoptosis resistance in cholangiocarcinoma.82
250433102015MicroRNA-25 promotes gastric cancer migration, invasion and proliferation by directly targeting transducer of ERBB2, 1 and correlates with poor survival.65
195418422010MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype.58
220765352012MiR-25 regulates apoptosis by targeting Bim in human ovarian cancer.56
234353732013MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7.53
224315892012MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme.46
240780042014MiR-25 promotes gastric cancer cells growth and motility by targeting RECK.37

Citation

Dessen P

MIR25 (microRNA 25)

Atlas Genet Cytogenet Oncol Haematol. 2008-04-01

Online version: http://atlasgeneticsoncology.org/gene/50097/mir25