MIR34C (microRNA 34c)

2008-09-01  

Identity

HGNC
LOCATION
11q23.1
LOCUSID
ALIAS
MIRN34C,miRNA34C,mir-34c

Other Information

Locus ID:

NCBI: 407042
MIM: 611375
HGNC: 31637
Ensembl: ENSG00000207562
miRBase:

Variants:

dbSNP: 407042
ClinVar: 407042
TCGA: ENSG00000207562
COSMIC: MIR34C

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
185196712008Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.216
202121542010p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication.86
184511452008Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence.84
219765042011MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34.84
203099402011A potentially functional polymorphism in the promoter region of miR-34b/c is associated with an increased risk for primary hepatocellular carcinoma.65
255414882015Inhibition of miR-34b and miR-34c enhances α-synuclein expression in Parkinson's disease.45
234234882013Regulation of microtubule-associated protein tau (MAPT) by miR-34c-5p determines the chemosensitivity of gastric cancer to paclitaxel.34
237207362013MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.34
250647032014Expression of miR-34c induces G2/M cell cycle arrest in breast cancer cells.32
235045542013Interactions of miR-34b/c and TP-53 polymorphisms on the risk of nasopharyngeal carcinoma.27

Citation

Dessen P

MIR34C (microRNA 34c)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50318/mir34c