MIR375 (microRNA 375)

2010-05-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
MIRN375,hsa-mir-375,miRNA375,mir-375

Other Information

Locus ID:

NCBI: 494324
MIM: 611173
HGNC: 31868
Ensembl: ENSG00000198973
miRBase:

Variants:

dbSNP: 494324
ClinVar: 494324
TCGA: ENSG00000198973
COSMIC: MIR375

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
205483342010MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2.129
220568812012MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo.121
209781872010Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells.97
202261662010MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties.92
218567452011miR-375 is activated by ASH1 and inhibits YAP1 in a lineage-dependent manner in lung cancer.45
217537662011Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC).43
255214812015Combinations of serum prostate-specific antigen and plasma expression levels of let-7c, miR-30c, miR-141, and miR-375 as potential better diagnostic biomarkers for prostate cancer.41
215931392011Downregulation of Sec23A protein by miRNA-375 in prostate carcinoma.37
250550442014Snail-regulated MiR-375 inhibits migration and invasion of gastric cancer cells by targeting JAK2.37
236853552013Overexpression of miR-10a and miR-375 and downregulation of YAP1 in medullary thyroid carcinoma.35

Citation

Dessen P

MIR375 (microRNA 375)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51502/mir375