MIR424 (microRNA 424)

2011-07-01  

Identity

HGNC
LOCATION
Xq26.3
LOCUSID
ALIAS
MIR322,MIRN424,hsa-mir-424,miRNA424,mir-424

Other Information

Locus ID:

NCBI: 494336
MIM: 300682
HGNC: 31881
Ensembl: ENSG00000284231
miRBase:

Variants:

dbSNP: 494336
ClinVar: 494336
TCGA: ENSG00000284231
COSMIC: MIR424

RNA/Proteins

References

Pubmed IDYearTitleCitations
209723352010Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis.160
288932652017Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression.132
204629532010MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A.93
218858512011MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1.92
224699832013Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer.91
178896712007The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.88
178896712007The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.88
271472252016miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint.60
268194132016LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR.52
196927022009miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.51

Citation

Dessen P

MIR424 (microRNA 424)

Atlas Genet Cytogenet Oncol Haematol. 2011-07-01

Online version: http://atlasgeneticsoncology.org/gene/52296/mir424