MIR491 (microRNA 491)

2010-08-01  

Identity

HGNC
MIR491
LOCATION
9p21.3
LOCUSID
574444
ALIAS
MIRN491,hsa-mir-491,mir-491

Other Information

Locus ID:

NCBI: 574444
HGNC: 32076
Ensembl: ENSG00000207609
miRBase:

Variants:

dbSNP: 574444
ClinVar: 574444
TCGA: ENSG00000207609
COSMIC: MIR491

RNA/Proteins

References

Pubmed IDYearTitleCitations
243359592014miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis.68
252997702014miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation.33
235192492012MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway.28
237254762013MicroRNA-491 is involved in metastasis of hepatocellular carcinoma by inhibitions of matrix metalloproteinase and epithelial to mesenchymal transition.18
257251942015miR-491-5p functions as a tumor suppressor by targeting JMJD2B in ERα-positive breast cancer.17
286486652017miR-491 Inhibits Osteosarcoma Lung Metastasis and Chemoresistance by Targeting αB-crystallin.17
251966412014Inhibition of TGF-β/SMAD3/NF-κB signaling by microRNA-491 is involved in arsenic trioxide-induced anti-angiogenesis in hepatocellular carcinoma cells.15
232576582013A functional polymorphism at miR-491-5p binding site in the 3'-UTR of MMP-9 gene confers increased risk for atherosclerotic cerebral infarction in a Chinese population.14
257493872015The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer.14
288447092017The miR-491-3p/Sp3/ABCB1 axis attenuates multidrug resistance of hepatocellular carcinoma.12

Citation

Dessen P

MIR491 (microRNA 491)

Atlas Genet Cytogenet Oncol Haematol. 2010-08-01

Online version: http://atlasgeneticsoncology.org/gene/51616/mir491