MIR494 (microRNA 494)

2012-03-01  

Identity

HGNC
MIR494
LOCATION
14q32.31
LOCUSID
574452
ALIAS
MIRN494,hsa-mir-494,mir-494

Other Information

Locus ID:

NCBI: 574452
MIM: 616036
HGNC: 32084
Ensembl: ENSG00000194717
miRBase:

Variants:

dbSNP: 574452
ClinVar: 574452
TCGA: ENSG00000194717
COSMIC: MIR494

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
230124232012MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.72
218598902011Competitive regulation of nucleolin expression by HuR and miR-494.50
239134422014MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer.44
248591612014Down-regulation of microRNA-494 via loss of SMAD4 increases FOXM1 and β-catenin signaling in pancreatic ductal adenocarcinoma cells.44
246440302014MicroRNA-494-3p targets CXCR4 to suppress the proliferation, invasion, and migration of prostate cancer.37
220429712011MicroRNA-494 downregulates KIT and inhibits gastrointestinal stromal tumor cell proliferation.36
256628492015miR-494-3p Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by PTEN/AKT Signaling in Human Glioblastoma Cells.33
220289192011Synergistic post-transcriptional regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 specific binding.30
252707232014miR‑494 is an independent prognostic factor and promotes cell migration and invasion in colorectal cancer by directly targeting PTEN.28
208078872010TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a.25

Citation

Dessen P

MIR494 (microRNA 494)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52617/mir494