MIR630 (microRNA 630)

2013-12-01  

Identity

HGNC
LOCATION
15q24.1
LOCUSID
ALIAS
MIRN630,hsa-mir-630

Other Information

Locus ID:

NCBI: 693215
HGNC: 32886
Ensembl: ENSG00000283798
miRBase:

Variants:

dbSNP: 693215
ClinVar: 693215
TCGA: ENSG00000283798
COSMIC: MIR630

RNA/Proteins

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Antiviral mechanism by IFN-stimulated genesREACTOMER-HSA-1169410
ISG15 antiviral mechanismREACTOMER-HSA-1169408

References

Pubmed IDYearTitleCitations
236754072013Upregulation of miR-150* and miR-630 induces apoptosis in pancreatic cancer cells by targeting IGF-1R.41
270407672016Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma.28
246557232014miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer.27
267253262016Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression.24
252552192014MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells.20
265955232016MiR-630 suppresses breast cancer progression by targeting metadherin.15
269408392016MiR-630 Inhibits Endothelial-Mesenchymal Transition by Targeting Slug in Traumatic Heterotopic Ossification.11
262633872015Novel Epigenetic CREB-miR-630 Signaling Axis Regulates Radiosensitivity in Colorectal Cancer.10
295076182018A low microRNA-630 expression confers resistance to tyrosine kinase inhibitors in EGFR-mutated lung adenocarcinomas via miR-630/YAP1/ERK feedback loop.10
257316702015miR-630 overexpression in hepatocellular carcinoma tissues is positively correlated with alpha-fetoprotein.7

Citation

Dessen P

MIR630 (microRNA 630)

Atlas Genet Cytogenet Oncol Haematol. 2013-12-01

Online version: http://atlasgeneticsoncology.org/gene/53631/mir630