MIR874 (microRNA 874)

2013-08-01  

Identity

HGNC
LOCATION
5q31.2
LOCUSID
ALIAS
MIRN874,hsa-mir-874,mir-874

Other Information

Locus ID:

NCBI: 100126343
HGNC: 33643
Ensembl: ENSG00000216009
miRBase:

Variants:

dbSNP: 100126343
ClinVar: 100126343
TCGA: ENSG00000216009
COSMIC: MIR874

RNA/Proteins

References

Pubmed IDYearTitleCitations
238009442014miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer.32
192407912009Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.24
252819242014MicroRNA-874 inhibits cell proliferation and induces apoptosis in human breast cancer by targeting CDK9.19
280768522017miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression.17
266310422016miR-874 suppresses the proliferation and metastasis of osteosarcoma by targeting E2F3.10
272212092016MicroRNA-874 inhibits growth, induces apoptosis and reverses chemoresistance in colorectal cancer by targeting X-linked inhibitor of apoptosis protein.9
300213552018LncRNA H19 functions as an Aquaporin 1 competitive endogenous RNA to regulate microRNA-874 expression in LPS sepsis.7
268758952016MiR-874 inhibits cell growth and induces apoptosis by targeting STAT3 in human colorectal cancer cells.6
291091432017MicroRNA-874-mediated inhibition of the major G1/S phase cyclin, CCNE1, is lost in osteosarcomas.5
303705782019microRNA-874 inhibition targeting STAT3 protects the heart from ischemia-reperfusion injury by attenuating cardiomyocyte apoptosis in a mouse model.4

Citation

Dessen P

MIR874 (microRNA 874)

Atlas Genet Cytogenet Oncol Haematol. 2013-08-01

Online version: http://atlasgeneticsoncology.org/gene/53733/mir874