MIRLET7A1 (microRNA let-7a-1)

2007-02-01  

Identity

HGNC
MIRLET7A1
LOCATION
9q22.32
LOCUSID
406881
ALIAS
LET7A1,MIRNLET7A1,let-7a-1

Other Information

Locus ID:

NCBI: 406881
MIM: 605386
HGNC: 31476
Ensembl: ENSG00000199165
miRBase:

Variants:

dbSNP: 406881
ClinVar: 406881
TCGA: ENSG00000199165
COSMIC: MIRLET7A1

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
198789812009An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation.594
176602972007A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection.168
191536032009Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7.150
230421162012LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.135
206398842010Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.128
214680302011Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family.116
249200702014H19 promotes pancreatic cancer metastasis by derepressing let-7's suppression on its target HMGA2-mediated EMT.111
216165242011Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation.105
179571442007Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2.92
223666862012Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells.89

Citation

Dessen P

MIRLET7A1 (microRNA let-7a-1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45695/mirlet7a1