MISP (mitotic spindle positioning)

2014-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
C19orf21,MISP1
FUSION GENES

Other Information

Locus ID:

NCBI: 126353
MIM: 615289
HGNC: 27000
Ensembl: ENSG00000099812

Variants:

dbSNP: 126353
ClinVar: 126353
TCGA: ENSG00000099812
COSMIC: MISP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099812ENST00000215582Q8IVT2

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
235090692013MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.25
235747152013The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells.7
296697402018Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation.5
244759242014Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.2
244759242014Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.2

Citation

Dessen P

MISP (mitotic spindle positioning)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70325/misp