MNDA (myeloid cell nuclear differentiation antigen)

2010-01-01  

Identity

HGNC
MNDA
LOCATION
1q23.1
LOCUSID
4332
ALIAS
PYHIN3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4332
MIM: 159553
HGNC: 7183
Ensembl: ENSG00000163563

Variants:

dbSNP: 4332
ClinVar: 4332
TCGA: ENSG00000163563
COSMIC: MNDA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163563ENST00000368141P41218
ENSG00000163563ENST00000368141Q5VUU6
ENSG00000163563ENST00000438394H0Y6P3

Expression (GTEx)

0
100
200
300
400
500
600
700
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
194747992009Identification of MNDA as a new marker for nodal marginal zone lymphoma.14
166514152006Dysregulated human myeloid nuclear differentiation antigen expression in myelodysplastic syndromes: evidence for a role in apoptosis.11
205952942010Association of IFI200 gene polymorphisms with susceptibility to systemic lupus erythematosus.3
157789722005Variable expression of human myeloid specific nuclear antigen MNDA in monocyte lineage cells in atherosclerosis.2
249252242014Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma.2
121120162002Retroviral mediated expression of the human myeloid nuclear antigen in a null cell line upregulates Dlk1 expression.1
261844522017Flow cytometry in the diagnosis of myelodysplastic syndromes and the value of myeloid nuclear differentiation antigen.1
201931162010Significance of myeloid antigen expression in precursor T lymphoblastic lymphoma.0
245570682014Purification, characterization and docking studies of the HIN domain of human myeloid nuclear differentiation antigen (MNDA).0
268225492016Value of Quantitative assessment of Myeloid Nuclear Differentiation Antigen expression and other flow cytometric parameters in the diagnosis of Myelodysplastic syndrome.0

Citation

Dessen P

MNDA (myeloid cell nuclear differentiation antigen)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51305/mnda