MOB1A (MOB kinase activator 1A)

2011-10-01  

Identity

HGNC
LOCATION
2p13.1
LOCUSID
ALIAS
C2orf6,MATS1,MOB1,MOBK1B,MOBKL1B,Mob4B
FUSION GENES

Other Information

Locus ID:

NCBI: 55233
MIM: 609281
HGNC: 16015
Ensembl: ENSG00000114978

Variants:

dbSNP: 55233
ClinVar: 55233
TCGA: ENSG00000114978
COSMIC: MOB1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114978ENST00000396049Q9H8S9

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
Hippo signalingKEGGhsa_M00683
Hippo signalingKEGGM00683
Signal TransductionREACTOMER-HSA-162582
Signaling by HippoREACTOMER-HSA-2028269
Hippo signaling pathway -multiple speciesKEGGko04392
Hippo signaling pathway -multiple speciesKEGGhsa04392

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
157665302005Control of cell proliferation and apoptosis by mob as tumor suppressor, mats.219
236520102013Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth.34
197391192010Molecular characterization of human homologs of yeast MOB1.22
283732982017MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.14
250313472014Seed sequence-matched controls reveal limitations of small interfering RNA knockdown in functional and structural studies of hepatitis C virus NS5A-MOBKL1B interaction.13
224545152012Human Mob1 proteins are required for cytokinesis by controlling microtubule stability.12
176116892007Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer.9
283732972017Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation.9
289477952017Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control.8
199552152010Mutual dependence of Mob1 and the chromosomal passenger complex for localization during mitosis.4

Citation

Dessen P

MOB1A (MOB kinase activator 1A)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52457/mob1a