MOB3B (MOB kinase activator 3B)

2016-05-01  

Identity

HGNC
LOCATION
9p21.2
LOCUSID
ALIAS
C9orf35,MOB1D,MOBKL2B
FUSION GENES

Other Information

Locus ID:

NCBI: 79817
MIM: 617652
HGNC: 23825
Ensembl: ENSG00000120162

Variants:

dbSNP: 79817
ClinVar: 79817
TCGA: ENSG00000120162
COSMIC: MOB3B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000120162ENST00000262244Q86TA1

Expression (GTEx)

0
5
10
15
20
25
30
35
40

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164713366Tumor necrosis factor alpha (TNF-alpha) inhibitorsChemicalClinicalAnnotationassociatedPD
PA443434Arthritis, RheumatoidDiseaseClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
185198262008Molecular genetics of successful smoking cessation: convergent genome-wide association study results.130
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
204234812010Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study.13
261309582015Lower Levels of Human MOB3B Are Associated with Prostate Cancer Susceptibility and Aggressive Clinicopathological Characteristics.5

Citation

Dessen P

MOB3B (MOB kinase activator 3B)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55743/mob3b