Atlas of Genetics and Cytogenetics in Oncology and Haematology


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MOCS3 (molybdenum cofactor synthesis 3)

Identity

Alias_symbol (synonym)UBA4
dJ914P20.3
Other alias
HGNC (Hugo) MOCS3
LocusID (NCBI) 27304
Atlas_Id 70363
Location 20q13.13  [Link to chromosome band 20q13]
Location_base_pair Starts at 50958814 and ends at 50961862 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MOCS3   15765
Cards
Entrez_Gene (NCBI)MOCS3  27304  molybdenum cofactor synthesis 3
AliasesUBA4
GeneCards (Weizmann)MOCS3
Ensembl hg19 (Hinxton)ENSG00000124217 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124217 [Gene_View]  ENSG00000124217 [Sequence]  chr20:50958814-50961862 [Contig_View]  MOCS3 [Vega]
ICGC DataPortalENSG00000124217
TCGA cBioPortalMOCS3
AceView (NCBI)MOCS3
Genatlas (Paris)MOCS3
WikiGenes27304
SOURCE (Princeton)MOCS3
Genetics Home Reference (NIH)MOCS3
Genomic and cartography
GoldenPath hg38 (UCSC)MOCS3  -     chr20:50958814-50961862 +  20q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MOCS3  -     20q13.13   [Description]    (hg19-Feb_2009)
GoldenPathMOCS3 - 20q13.13 [CytoView hg19]  MOCS3 - 20q13.13 [CytoView hg38]
ImmunoBaseENSG00000124217
Mapping of homologs : NCBIMOCS3 [Mapview hg19]  MOCS3 [Mapview hg38]
OMIM609277   
Gene and transcription
Genbank (Entrez)AF102544 AI942426 BC015939 BG105185 BQ188547
RefSeq transcript (Entrez)NM_014484
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MOCS3
Cluster EST : UnigeneHs.736268 [ NCBI ]
CGAP (NCI)Hs.736268
Alternative Splicing GalleryENSG00000124217
Gene ExpressionMOCS3 [ NCBI-GEO ]   MOCS3 [ EBI - ARRAY_EXPRESS ]   MOCS3 [ SEEK ]   MOCS3 [ MEM ]
Gene Expression Viewer (FireBrowse)MOCS3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27304
GTEX Portal (Tissue expression)MOCS3
Human Protein AtlasENSG00000124217-MOCS3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95396   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95396  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95396
Splice isoforms : SwissVarO95396
PhosPhoSitePlusO95396
Domaine pattern : Prosite (Expaxy)RHODANESE_3 (PS50206)   
Domains : Interpro (EBI)MOCS3/Uba4    Rhodanese-like_dom    Rhodanese-like_dom_sf    ThiF_NAD_FAD-bd    Ubiquitin-activating_enz   
Domain families : Pfam (Sanger)Rhodanese (PF00581)    ThiF (PF00899)   
Domain families : Pfam (NCBI)pfam00581    pfam00899   
Domain families : Smart (EMBL)RHOD (SM00450)  
Conserved Domain (NCBI)MOCS3
DMDM Disease mutations27304
Blocks (Seattle)MOCS3
PDB (RSDB)3I2V   
PDB Europe3I2V   
PDB (PDBSum)3I2V   
PDB (IMB)3I2V   
Structural Biology KnowledgeBase3I2V   
SCOP (Structural Classification of Proteins)3I2V   
CATH (Classification of proteins structures)3I2V   
SuperfamilyO95396
Human Protein Atlas [tissue]ENSG00000124217-MOCS3 [tissue]
Peptide AtlasO95396
HPRD10092
IPIIPI00004489   
Protein Interaction databases
DIP (DOE-UCLA)O95396
IntAct (EBI)O95396
FunCoupENSG00000124217
BioGRIDMOCS3
STRING (EMBL)MOCS3
ZODIACMOCS3
Ontologies - Pathways
QuickGOO95396
Ontology : AmiGOtRNA wobble uridine modification  tRNA wobble position uridine thiolation  thiosulfate sulfurtransferase activity  thiosulfate sulfurtransferase activity  protein binding  ATP binding  cytoplasm  cytosol  cytosol  Mo-molybdopterin cofactor biosynthetic process  nucleotidyltransferase activity  nucleotidyltransferase activity  sulfurtransferase activity  enzyme active site formation via cysteine modification to L-cysteine persulfide  molybdopterin cofactor biosynthetic process  protein urmylation  tRNA thio-modification  URM1 activating enzyme activity  URM1 activating enzyme activity  metal ion binding  molybdopterin-synthase sulfurtransferase activity  molybdopterin-synthase adenylyltransferase activity  
Ontology : EGO-EBItRNA wobble uridine modification  tRNA wobble position uridine thiolation  thiosulfate sulfurtransferase activity  thiosulfate sulfurtransferase activity  protein binding  ATP binding  cytoplasm  cytosol  cytosol  Mo-molybdopterin cofactor biosynthetic process  nucleotidyltransferase activity  nucleotidyltransferase activity  sulfurtransferase activity  enzyme active site formation via cysteine modification to L-cysteine persulfide  molybdopterin cofactor biosynthetic process  protein urmylation  tRNA thio-modification  URM1 activating enzyme activity  URM1 activating enzyme activity  metal ion binding  molybdopterin-synthase sulfurtransferase activity  molybdopterin-synthase adenylyltransferase activity  
NDEx NetworkMOCS3
Atlas of Cancer Signalling NetworkMOCS3
Wikipedia pathwaysMOCS3
Orthology - Evolution
OrthoDB27304
GeneTree (enSembl)ENSG00000124217
Phylogenetic Trees/Animal Genes : TreeFamMOCS3
HOGENOMO95396
Homologs : HomoloGeneMOCS3
Homology/Alignments : Family Browser (UCSC)MOCS3
Gene fusions - Rearrangements
Fusion : QuiverMOCS3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMOCS3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MOCS3
dbVarMOCS3
ClinVarMOCS3
1000_GenomesMOCS3 
Exome Variant ServerMOCS3
ExAC (Exome Aggregation Consortium)ENSG00000124217
GNOMAD BrowserENSG00000124217
Varsome BrowserMOCS3
Genetic variants : HAPMAP27304
Genomic Variants (DGV)MOCS3 [DGVbeta]
DECIPHERMOCS3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMOCS3 
Mutations
ICGC Data PortalMOCS3 
TCGA Data PortalMOCS3 
Broad Tumor PortalMOCS3
OASIS PortalMOCS3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMOCS3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMOCS3
Mutations and Diseases : HGMDMOCS3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MOCS3
DgiDB (Drug Gene Interaction Database)MOCS3
DoCM (Curated mutations)MOCS3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MOCS3 (select a term)
intoGenMOCS3
Cancer3DMOCS3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609277   
Orphanet
DisGeNETMOCS3
MedgenMOCS3
Genetic Testing Registry MOCS3
NextProtO95396 [Medical]
TSGene27304
GENETestsMOCS3
Target ValidationMOCS3
Huge Navigator MOCS3 [HugePedia]
snp3D : Map Gene to Disease27304
BioCentury BCIQMOCS3
ClinGenMOCS3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27304
Chemical/Pharm GKB GenePA30904
Clinical trialMOCS3
Miscellaneous
canSAR (ICR)MOCS3 (select the gene name)
DataMed IndexMOCS3
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMOCS3
EVEXMOCS3
GoPubMedMOCS3
iHOPMOCS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Sep 3 15:56:27 CEST 2019

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