MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking)

2014-11-01  

Identity

HGNC
LOCATION
12q14.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 23041
MIM: 616822
HGNC: 29177
Ensembl: ENSG00000061987

Variants:

dbSNP: 23041
ClinVar: 23041
TCGA: ENSG00000061987
COSMIC: MON2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000061987ENST00000393629Q7Z3U7
ENSG00000061987ENST00000393630Q7Z3U7
ENSG00000061987ENST00000546600Q7Z3U7
ENSG00000061987ENST00000547095F8VZV6
ENSG00000061987ENST00000549286F8VQS2
ENSG00000061987ENST00000552115F8VZV1
ENSG00000061987ENST00000552738Q7Z3U7
ENSG00000061987ENST00000641654A0A286YFF8

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
184183882008Yeast and human Ysl2p/hMon2 interact with Gga adaptors and mediate their subcellular distribution.14
242853432013Mammalian Mon2/Ysl2 regulates endosome-to-Golgi trafficking but possesses no guanine nucleotide exchange activity toward Arl1 GTPase.9
214508272011The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles.8
302139402018SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.4

Citation

Dessen P

MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70370/mon2