MOS (MOS proto-oncogene, serine/threonine kinase)

2003-02-01 Affiliation

Identity

HGNC

MOS

LOCATION

8q12.1

LOCUSID

4342

ALIAS

MSV

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 4342
MIM: 190060
HGNC: 7199
Ensembl: ENSG00000172680

Variants:

dbSNP: 4342
ClinVar: 4342
TCGA: ENSG00000172680
COSMIC: MOS

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000172680	ENST00000311923	P00540

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
MAPK signaling pathway	KEGG	ko04010
Regulation of actin cytoskeleton	KEGG	ko04810
Progesterone-mediated oocyte maturation	KEGG	ko04914
MAPK signaling pathway	KEGG	hsa04010
Regulation of actin cytoskeleton	KEGG	hsa04810
Progesterone-mediated oocyte maturation	KEGG	hsa04914
Oocyte meiosis	KEGG	ko04114
Oocyte meiosis	KEGG	hsa04114
MAPK (ERK1/2) signaling	KEGG	hsa_M00687
MAPK (ERK1/2) signaling	KEGG	M00687

References

Pubmed ID	Year	Title	Citations
20186124	2010	Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.	72
17410130	2007	A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs.	40
16401344	2006	Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe.	38
25512530	2014	Genetic modifiers of EGFR dependence in non-small cell lung cancer.	27
20546612	2010	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	19
23595635	2013	Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study.	17
22252584	2012	Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae.	13
18550795	2008	Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.	12
18246541	2008	Mos 3' UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation.	10
11180847	2000	The Mos/MAPK pathway is involved in metaphase II arrest as a cytostatic factor but is neither necessary nor sufficient for initiating oocyte maturation in goldfish.	7

Citation

Dessen P

MOS (MOS proto-oncogene, serine/threonine kinase)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41414/mos