MPEG1 (macrophage expressed 1)

2014-11-01  

Identity

HGNC
MPEG1
LOCATION
11q12.1
LOCUSID
219972
ALIAS
IMD77,MPG1,MPS1,Mpg-1,P-2

Other Information

Locus ID:

NCBI: 219972
MIM: 610390
HGNC: 29619
Ensembl: ENSG00000197629

Variants:

dbSNP: 219972
ClinVar: 219972
TCGA: ENSG00000197629
COSMIC: MPEG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197629ENST00000361050Q2M385

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
237536252013Perforin-2 restricts growth of Chlamydia trachomatis in macrophages.22
264187462015Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2.16
263075492015Perforin-2/Mpeg1 and other pore-forming proteins throughout evolution.13
287053752017Regulation of expression and trafficking of perforin-2 by LPS and TNF-α.3

Citation

Dessen P

MPEG1 (macrophage expressed 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70389/mpeg1