MPHOSPH6 (M-phase phosphoprotein 6)

2014-11-01  

Identity

HGNC
LOCATION
16q23.3
LOCUSID
ALIAS
MPP,MPP-6,MPP6
FUSION GENES

Other Information

Locus ID:

NCBI: 10200
MIM: 605500
HGNC: 7214
Ensembl: ENSG00000135698

Variants:

dbSNP: 10200
ClinVar: 10200
TCGA: ENSG00000135698
COSMIC: MPHOSPH6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135698ENST00000258169Q99547
ENSG00000135698ENST00000563100H3BNT4
ENSG00000135698ENST00000563504H3BSB3
ENSG00000135698ENST00000568016H3BU96
ENSG00000135698ENST00000569021H3BNK8

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
117191862001AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.347
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
163968332005MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation.40

Citation

Dessen P

MPHOSPH6 (M-phase phosphoprotein 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70391/mphosph6