Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MPP1 (membrane palmitoylated protein 1)

Identity

Alias_namesDXS552E
membrane protein, palmitoylated 1 (55kD)
membrane protein, palmitoylated 1, 55kDa
membrane protein, palmitoylated 1
Alias_symbol (synonym)PEMP
Other aliasAAG12
EMP55
MRG1
HGNC (Hugo) MPP1
LocusID (NCBI) 4354
Atlas_Id 41420
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 154778684 and ends at 154805527 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MPP1 (Xq28) / MPP1 (Xq28)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MPP1   7219
Cards
Entrez_Gene (NCBI)MPP1  4354  membrane palmitoylated protein 1
AliasesAAG12; DXS552E; EMP55; MRG1; 
PEMP
GeneCards (Weizmann)MPP1
Ensembl hg19 (Hinxton)ENSG00000130830 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130830 [Gene_View]  ENSG00000130830 [Sequence]  chrX:154778684-154805527 [Contig_View]  MPP1 [Vega]
ICGC DataPortalENSG00000130830
TCGA cBioPortalMPP1
AceView (NCBI)MPP1
Genatlas (Paris)MPP1
WikiGenes4354
SOURCE (Princeton)MPP1
Genetics Home Reference (NIH)MPP1
Genomic and cartography
GoldenPath hg38 (UCSC)MPP1  -     chrX:154778684-154805527 -  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MPP1  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathMPP1 - Xq28 [CytoView hg19]  MPP1 - Xq28 [CytoView hg38]
ImmunoBaseENSG00000130830
Mapping of homologs : NCBIMPP1 [Mapview hg19]  MPP1 [Mapview hg38]
OMIM305360   
Gene and transcription
Genbank (Entrez)AK093702 AK223396 AK290246 AK303111 AK304538
RefSeq transcript (Entrez)NM_001166460 NM_001166461 NM_001166462 NM_002436
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MPP1
Cluster EST : UnigeneHs.496984 [ NCBI ]
CGAP (NCI)Hs.496984
Alternative Splicing GalleryENSG00000130830
Gene ExpressionMPP1 [ NCBI-GEO ]   MPP1 [ EBI - ARRAY_EXPRESS ]   MPP1 [ SEEK ]   MPP1 [ MEM ]
Gene Expression Viewer (FireBrowse)MPP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4354
GTEX Portal (Tissue expression)MPP1
Human Protein AtlasENSG00000130830-MPP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ00013   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ00013  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ00013
Splice isoforms : SwissVarQ00013
PhosPhoSitePlusQ00013
Domaine pattern : Prosite (Expaxy)GUANYLATE_KINASE_1 (PS00856)    GUANYLATE_KINASE_2 (PS50052)    PDZ (PS50106)    SH3 (PS50002)   
Domains : Interpro (EBI)GK/Ca_channel_bsu    Guanylate_kin-like_dom    Guanylate_kinase_CS    MPP1_SH3    P-loop_NTPase    PDZ    PDZ_sf    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)Guanylate_kin (PF00625)    PDZ (PF00595)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam00625    pfam00595    pfam07653   
Domain families : Smart (EMBL)GuKc (SM00072)  PDZ (SM00228)  SH3 (SM00326)  
Conserved Domain (NCBI)MPP1
DMDM Disease mutations4354
Blocks (Seattle)MPP1
PDB (RSDB)2EJY    2EV8    3NEY   
PDB Europe2EJY    2EV8    3NEY   
PDB (PDBSum)2EJY    2EV8    3NEY   
PDB (IMB)2EJY    2EV8    3NEY   
Structural Biology KnowledgeBase2EJY    2EV8    3NEY   
SCOP (Structural Classification of Proteins)2EJY    2EV8    3NEY   
CATH (Classification of proteins structures)2EJY    2EV8    3NEY   
SuperfamilyQ00013
Human Protein Atlas [tissue]ENSG00000130830-MPP1 [tissue]
Peptide AtlasQ00013
HPRD02370
IPIIPI00215610   IPI00640916   IPI00853348   IPI00853558   IPI00853284   IPI00879493   IPI00878309   IPI00927393   
Protein Interaction databases
DIP (DOE-UCLA)Q00013
IntAct (EBI)Q00013
FunCoupENSG00000130830
BioGRIDMPP1
STRING (EMBL)MPP1
ZODIACMPP1
Ontologies - Pathways
QuickGOQ00013
Ontology : AmiGOguanylate kinase activity  protein binding  intracellular  cytosol  plasma membrane  signal transduction  membrane  nuclear speck  cortical cytoskeleton  stereocilium  GMP metabolic process  GDP metabolic process  regulation of neutrophil chemotaxis  
Ontology : EGO-EBIguanylate kinase activity  protein binding  intracellular  cytosol  plasma membrane  signal transduction  membrane  nuclear speck  cortical cytoskeleton  stereocilium  GMP metabolic process  GDP metabolic process  regulation of neutrophil chemotaxis  
NDEx NetworkMPP1
Atlas of Cancer Signalling NetworkMPP1
Wikipedia pathwaysMPP1
Orthology - Evolution
OrthoDB4354
GeneTree (enSembl)ENSG00000130830
Phylogenetic Trees/Animal Genes : TreeFamMPP1
HOGENOMQ00013
Homologs : HomoloGeneMPP1
Homology/Alignments : Family Browser (UCSC)MPP1
Gene fusions - Rearrangements
Fusion : QuiverMPP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMPP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MPP1
dbVarMPP1
ClinVarMPP1
1000_GenomesMPP1 
Exome Variant ServerMPP1
ExAC (Exome Aggregation Consortium)ENSG00000130830
GNOMAD BrowserENSG00000130830
Varsome BrowserMPP1
Genetic variants : HAPMAP4354
Genomic Variants (DGV)MPP1 [DGVbeta]
DECIPHERMPP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMPP1 
Mutations
ICGC Data PortalMPP1 
TCGA Data PortalMPP1 
Broad Tumor PortalMPP1
OASIS PortalMPP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMPP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMPP1
Mutations and Diseases : HGMDMPP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch MPP1
DgiDB (Drug Gene Interaction Database)MPP1
DoCM (Curated mutations)MPP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MPP1 (select a term)
intoGenMPP1
Cancer3DMPP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM305360   
Orphanet
DisGeNETMPP1
MedgenMPP1
Genetic Testing Registry MPP1
NextProtQ00013 [Medical]
TSGene4354
GENETestsMPP1
Target ValidationMPP1
Huge Navigator MPP1 [HugePedia]
snp3D : Map Gene to Disease4354
BioCentury BCIQMPP1
ClinGenMPP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4354
Chemical/Pharm GKB GenePA30924
Clinical trialMPP1
Miscellaneous
canSAR (ICR)MPP1 (select the gene name)
DataMed IndexMPP1
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMPP1
EVEXMPP1
GoPubMedMPP1
iHOPMPP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:56:17 CET 2019
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