MPPE1 (metallophosphoesterase 1)

2014-11-01  

Identity

HGNC
MPPE1
LOCATION
18p11.21
LOCUSID
65258
ALIAS
Cdc1,PGAP5
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 65258
MIM: 611900
HGNC: 15988
Ensembl: ENSG00000154889

Variants:

dbSNP: 65258
ClinVar: 65258
TCGA: ENSG00000154889
COSMIC: MPPE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154889ENST00000309976Q53F39
ENSG00000154889ENST00000317235Q53F39
ENSG00000154889ENST00000317251A0A0C4DH11
ENSG00000154889ENST00000344987A0A0A0MR93
ENSG00000154889ENST00000496196Q53F39
ENSG00000154889ENST00000586844K7ERI3
ENSG00000154889ENST00000587724K7ELZ7
ENSG00000154889ENST00000588072Q53F39
ENSG00000154889ENST00000588103K7ER13
ENSG00000154889ENST00000588186K7EQV4
ENSG00000154889ENST00000588191K7EQ70
ENSG00000154889ENST00000589267K7EJU0
ENSG00000154889ENST00000589859K7EQ74
ENSG00000154889ENST00000590501K7ESB8
ENSG00000154889ENST00000592306K7EIQ0
ENSG00000154889ENST00000592331K7EM03
ENSG00000154889ENST00000592977K7ES91
ENSG00000154889ENST00000593001A0A075B777

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198370362009GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi.40
193285582009Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.11
119789712001cDNA cloning, genomic organization and expression of the novel human metallophosphoesterase gene MPPE1 on chromosome 18p11.2.2
198599032010Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder.1
198599032010Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder.1

Citation

Dessen P

MPPE1 (metallophosphoesterase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70395/mppe1