Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MRPL11 (mitochondrial ribosomal protein L11)

Identity

Other aliasCGI-113
L11MT
MRP-L11
HGNC (Hugo) MRPL11
LocusID (NCBI) 65003
Atlas_Id 70433
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 66435075 and ends at 66438848 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MRPL11 (11q13.2) / MRFAP1 (4p16.1)MRPL11 (11q13.2) / ST8SIA1 (12p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MRPL11   14042
Cards
Entrez_Gene (NCBI)MRPL11  65003  mitochondrial ribosomal protein L11
AliasesCGI-113; L11MT; MRP-L11
GeneCards (Weizmann)MRPL11
Ensembl hg19 (Hinxton)ENSG00000174547 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174547 [Gene_View]  ENSG00000174547 [Sequence]  chr11:66435075-66438848 [Contig_View]  MRPL11 [Vega]
ICGC DataPortalENSG00000174547
TCGA cBioPortalMRPL11
AceView (NCBI)MRPL11
Genatlas (Paris)MRPL11
WikiGenes65003
SOURCE (Princeton)MRPL11
Genetics Home Reference (NIH)MRPL11
Genomic and cartography
GoldenPath hg38 (UCSC)MRPL11  -     chr11:66435075-66438848 -  11q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MRPL11  -     11q13.2   [Description]    (hg19-Feb_2009)
GoldenPathMRPL11 - 11q13.2 [CytoView hg19]  MRPL11 - 11q13.2 [CytoView hg38]
ImmunoBaseENSG00000174547
Mapping of homologs : NCBIMRPL11 [Mapview hg19]  MRPL11 [Mapview hg38]
OMIM611826   
Gene and transcription
Genbank (Entrez)AB049638 AF151871 AK127603 AK223112 AK290084
RefSeq transcript (Entrez)NM_016050 NM_170738 NM_170739
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MRPL11
Cluster EST : UnigeneHs.418450 [ NCBI ]
CGAP (NCI)Hs.418450
Alternative Splicing GalleryENSG00000174547
Gene ExpressionMRPL11 [ NCBI-GEO ]   MRPL11 [ EBI - ARRAY_EXPRESS ]   MRPL11 [ SEEK ]   MRPL11 [ MEM ]
Gene Expression Viewer (FireBrowse)MRPL11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65003
GTEX Portal (Tissue expression)MRPL11
Human Protein AtlasENSG00000174547-MRPL11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3B7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3B7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3B7
Splice isoforms : SwissVarQ9Y3B7
PhosPhoSitePlusQ9Y3B7
Domains : Interpro (EBI)Ribosomal_L11/L12    Ribosomal_L11/L12_N_sf    Ribosomal_L11_bac-typ    Ribosomal_L11_C    Ribosomal_L11_C_sf    Ribosomal_L11_N   
Domain families : Pfam (Sanger)Ribosomal_L11 (PF00298)    Ribosomal_L11_N (PF03946)   
Domain families : Pfam (NCBI)pfam00298    pfam03946   
Domain families : Smart (EMBL)RL11 (SM00649)  
Conserved Domain (NCBI)MRPL11
DMDM Disease mutations65003
Blocks (Seattle)MRPL11
PDB (RSDB)3J7Y    3J9M    5OOL    5OOM   
PDB Europe3J7Y    3J9M    5OOL    5OOM   
PDB (PDBSum)3J7Y    3J9M    5OOL    5OOM   
PDB (IMB)3J7Y    3J9M    5OOL    5OOM   
Structural Biology KnowledgeBase3J7Y    3J9M    5OOL    5OOM   
SCOP (Structural Classification of Proteins)3J7Y    3J9M    5OOL    5OOM   
CATH (Classification of proteins structures)3J7Y    3J9M    5OOL    5OOM   
SuperfamilyQ9Y3B7
Human Protein Atlas [tissue]ENSG00000174547-MRPL11 [tissue]
Peptide AtlasQ9Y3B7
HPRD14739
IPIIPI00007001   IPI00377233   IPI00982504   IPI00983181   IPI00333848   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3B7
IntAct (EBI)Q9Y3B7
FunCoupENSG00000174547
BioGRIDMRPL11
STRING (EMBL)MRPL11
ZODIACMRPL11
Ontologies - Pathways
QuickGOQ9Y3B7
Ontology : AmiGOribosomal large subunit assembly  RNA binding  structural constituent of ribosome  structural constituent of ribosome  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial ribosome  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  translation  translation  large ribosomal subunit  rRNA binding  mitochondrial translational elongation  mitochondrial translational termination  large ribosomal subunit rRNA binding  
Ontology : EGO-EBIribosomal large subunit assembly  RNA binding  structural constituent of ribosome  structural constituent of ribosome  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial ribosome  mitochondrial large ribosomal subunit  mitochondrial large ribosomal subunit  translation  translation  large ribosomal subunit  rRNA binding  mitochondrial translational elongation  mitochondrial translational termination  large ribosomal subunit rRNA binding  
Pathways : BIOCARTAMechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) [Genes]   
NDEx NetworkMRPL11
Atlas of Cancer Signalling NetworkMRPL11
Wikipedia pathwaysMRPL11
Orthology - Evolution
OrthoDB65003
GeneTree (enSembl)ENSG00000174547
Phylogenetic Trees/Animal Genes : TreeFamMRPL11
HOGENOMQ9Y3B7
Homologs : HomoloGeneMRPL11
Homology/Alignments : Family Browser (UCSC)MRPL11
Gene fusions - Rearrangements
Fusion : QuiverMRPL11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMRPL11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MRPL11
dbVarMRPL11
ClinVarMRPL11
1000_GenomesMRPL11 
Exome Variant ServerMRPL11
ExAC (Exome Aggregation Consortium)ENSG00000174547
GNOMAD BrowserENSG00000174547
Varsome BrowserMRPL11
Genetic variants : HAPMAP65003
Genomic Variants (DGV)MRPL11 [DGVbeta]
DECIPHERMRPL11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMRPL11 
Mutations
ICGC Data PortalMRPL11 
TCGA Data PortalMRPL11 
Broad Tumor PortalMRPL11
OASIS PortalMRPL11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMRPL11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMRPL11
Mutations and Diseases : HGMDMRPL11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch MRPL11
DgiDB (Drug Gene Interaction Database)MRPL11
DoCM (Curated mutations)MRPL11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MRPL11 (select a term)
intoGenMRPL11
Cancer3DMRPL11(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611826   
Orphanet
DisGeNETMRPL11
MedgenMRPL11
Genetic Testing Registry MRPL11
NextProtQ9Y3B7 [Medical]
TSGene65003
GENETestsMRPL11
Target ValidationMRPL11
Huge Navigator MRPL11 [HugePedia]
snp3D : Map Gene to Disease65003
BioCentury BCIQMRPL11
ClinGenMRPL11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65003
Chemical/Pharm GKB GenePA30940
Clinical trialMRPL11
Miscellaneous
canSAR (ICR)MRPL11 (select the gene name)
DataMed IndexMRPL11
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMRPL11
EVEXMRPL11
GoPubMedMRPL11
iHOPMRPL11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:56:41 CEST 2019
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