MRPL41 (mitochondrial ribosomal protein L41)

2007-02-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
BMRP,MRP-L27,MRPL27,PIG3,RPML27

Other Information

Locus ID:

NCBI: 64975
MIM: 611846
HGNC: 14492
Ensembl: ENSG00000182154

Variants:

dbSNP: 64975
ClinVar: 64975
TCGA: ENSG00000182154
COSMIC: MRPL41

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182154ENST00000371443Q8IXM3

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
160247962005Mitochondrial ribosomal protein L41 suppresses cell growth in association with p53 and p27Kip1.32
162569472005Mitochondrial ribosomal protein L41 mediates serum starvation-induced cell-cycle arrest through an increase of p21(WAF1/CIP1).17
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
155479502005BMRP is a Bcl-2 binding protein that induces apoptosis.11
227115032012Identification of a motif in BMRP required for interaction with Bcl-2 by site-directed mutagenesis studies.4
241602662013Nuclear-encoded mitochondrial MTO1 and MRPL41 are regulated in an opposite epigenetic mode based on estrogen receptor status in breast cancer.4
212538512011Deletion mutational analysis of BMRP, a pro-apoptotic protein that binds to Bcl-2.1

Citation

Dessen P

MRPL41 (mitochondrial ribosomal protein L41)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46499/mrpl41